Cancer Biology Journal Club, The University of Iowa
Spring 2018, 11:30-12:30, Every Other Monday, Room B180, Med Labs
Contact: douglas-spitz@uiowa.edu Tel 319/335-8019

January 22, 2018
Presenter: Kelly Falls
Paper: Skrott Z, Mistrik M, Andersen KK, Friis S, Majera D, Gursky J, Ozdian T, Bartkova J, Turi Z, Moudry P, Kraus M, Michalova M, Vaclavkova J, Dzubak P, Vrobel I, Pouckova P, Sedlacek J, Miklovicova A, Kutt A, Li J, Mattova J, Driessen C, Dou QP, Olsen J, Hajduch M, Cvek B, Deshaies RJ, Bartek J. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.Nature. 2017 Dec 14;552(7684):194-199. PMID: 29211715; PMCID: PMC5730499.
doi: 10.1038/nature25016.

February 5, 2018
Presenter: Adrienne Gibson
Paper: Polireddy K, Dong R, Reed G, Yu J, Chen P, Williamson S, Violet PC, Pessetto Z, Godwin AK, Fan F, Levine M, Drisko JA, Chen Q. High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study. Sci Rep. 2017 Dec 7;7(1):17188. PMCID: PMC5719364. PMID: 29215048
doi:10.1038/s41598-017-17568-8.

February 19, 2018
Presenter: Dr. Douglas Spitz
Paper: Khan AA, Paget JT, McLaughlin M, Kyula JN, Wilkinson MJ, Pencavel T, Mansfield D, Roulstone V, Seth R, Halle M, Somaiah N, Boult JKR, Robinson SP, Pandha HS, Vile RG, Melcher AA, Harris PA, Harrington KJ. Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues. Sci Transl Med. 2018 Jan 24;10(425). pii: eaar2041. PMID: 29367346.
doi: 10.1126/scitranslmed.aar2041

Supplementary Materials for Paper:
Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues.
www.sciencetranslationalmedicine.org/cgi/content/full/10/425/eaar2041/DC1

March 5, 2018
Presenter: Michelle Tamplin
Paper:Behling K, Maguire WF, Di Gialleonardo V, Heeb LE, Hassan IF, Veach DR, Keshari KR, Gutin PH, Scheinberg DA, McDevitt MR. Remodeling the Vascular Microenvironment of Glioblastoma with α-Particles. J Nucl Med. 2016 Nov;57(11):1771-1777. PMCID: PMC5093034.
doi: 10.2967/jnumed.116.173559

March 19, 2018
Presenter: Dr. Frederick Domann
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April 2, 2018
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April 16, 2018
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April 30 2018
Presenter: Paul Akhenblit
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