Free Radical Journal Club
The University of Iowa
Room B180, Med Labs
Contact: email@example.com Tel 319/335-6749
August 26, 1998
Presenter: Garry R. Buettner, PhD
Paper: Maret W; Vallee BL. (1998) Thiolate ligands in metallothionein confer redox activity on zinc clusters. PNAS 95: 3478-3482.
September 02, 1998
Presenter: Michael McCormick, PhD
Paper: Van Duijn Martijn M et al. (1998) Ascorbate stimulates ferricyanide reduction in HL-60 cells through a mechanism distinct from the NADH-dependent plasma membrane reductase. J Biol Chem 273: 13415-13420.
September 09, 1998
David Hall, PhD
Parkes TL et al. (1998) Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. Nature Genetics 19:171-174.
September 16, 1998
Presenter: Larry Oberley, PhD
Paper: Kinscherf Ralf et al. (1998) Apoptosis caused by oxidized LDL is manganese superoxide dismutase and p53 dependent. FASEB J 12: 461-467.
Kinscherf Ralf et al. (1997) Induction of mitochondrial manganese superoxide dismutase in macrophages by oxidized LDL: its relevance in atherosclerosis of humans and heritable hyperlipidemic rabbits. FASEB J 11: 1317-1327.
September 23, 1998
Presenter: Rick Domann, PhD
Paper: Gowen LC et al. (1998) BRCA1 required for transcription-coupled repair of oxidative damage. Science 281: 1009-1012.
September 30, 1998
Presenter: Shawn Flanagan, PhD
Paper: Teixeira HD et al. (1998) Lower intracellular hydrogen peroxide levels in cells overexpressing CuZn-superoxide dismutase. PNAS 95: 7872-7875.
October 07, 1998
Presenter: Ying Zhang
Paper: Majima HJ et al. (1998) Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkaline-induced cell death. J Biol Chem 273: 8217-8224.
October 14, 1998
Presenter: Eric Kelley
Paper: Pahan K et al. (1998) N-acetyl cysteine inhibits induction of NO production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes. Free Rad Biol Med 24: 39-48.
October 21, 1998
Presenter: Jeff Kirsch
Paper: Joneson T and Bar-Sagi D. (1998) A Rac1 effector site controlling mitogenesis through superoxide production. J Biological Chem 273: 17991-17994.
October 28, 1998
Presenter: Shimin Wei
Paper: Moutet M et al. (1998) Glutathione peroxidase mimics prevent TNFa - and neutrophil-induced endothelial alterations. Free Rad Biol Med 25: 270-281.
November 04, 1998
Presenter: Chunhong Zhu
Paper: Jackson RM et al. (1998) Peroxynitrite modulates MnSOD gene expression in lung epithelial cells. Free Rad Biol Med 25: 463-472.
November 11, 1998
Presenter: Meredith Preuss
Paper: Li Y et al. (1997) A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 19: 453-463.
November 18, 1998
Presenter: Hong Wang
Paper: Vanden Hoek TL et al. (1998) Reactive oxygen species released from mitochondria during brief hypoxida induce preconditioning in cardiomyocytes. J Biol Chem 273: 18092-18098.
November 25, 1998
No presenter: Thanksgiving Break
December 02, 1998
Presenter: Tao Yan, PhD
Paper: Chandel NS et al. (1998) Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. PNAS 95: 11715-11720.
December 09, 1998
Presenter: Oyebode Olakanmi, PhD
Paper: Horwitz LD et al. (1998) Lipophilic siderophores of Mycobacterium tuberculosis prevent cardiac reperfusion injury. PNAS 95: 5263-5268.
December 18, 1998
Presenter: Stephen Hempel, PhD
Paper: Ichijo H et al. (1997) Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275: 90-94.
Gotoh Y and Cooper JA. (1998) Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-a signal transduction. J Biol Chem 273: 17477-17482.