Cancer Biology Journal Club, The University of Iowa
Spring 2020, 11:30-12:30, Every Other Monday, Room B180, Med Labs
Contact: douglas-spitz@uiowa.edu Tel 319/335-8019

January 27, 2020
Presenter:  Dr. Prabhat C. Goswami
Paper:  Nagdas S, Kashatus JA, Nascimento A, Hussain SS, Trainor RE, Pollock SR, Adair SJ, Michaels AD, Sesaki H, Stelow EB, Bauer TW, Kashatus DF. Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth. Cell Rep. 2019 Aug 13;28(7):1845-1859.e5. PMID:31412251; PMCID: PMC6711191.
doi: 10.1016/j.celrep.2019.07.031.
 

February 10, 2020
Presenter: Yuna Bayanbold
Paper: Weber RA, Yen FS, Nicholson SPV, Alwaseem H, Bayraktar EC, Alam M, Timson RC, La K, Abu-Remaileh M, Molina H, Birsoy K. Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation. Mol Cell. 2020 Jan 15. pii: S1097-2765(20)30003-4. PMID: 31983508.
doi: 10.1016/j.molcel.2020.01.003.
 

February 24, 2020
Presenter: Sam Rodman
Paper: Hanley CJ, Mellone M, Ford K, Thirdborough SM, Mellows T, Frampton SJ, Smith DM, Harden E, Szyndralewiez C, Bullock M, Noble F, Moutasim KA, King EV, Vijayanand P, Mirnezami AH, Underwood TJ, Ottensmeier CH, Thomas GJ. Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4. J Natl Cancer Inst. 2018 Jan 1;110(1). PMID: 28922779;
doi: 10.1093/jnci/djx121.
 

March 9, 2020
Presenter:  Rory Carroll
Paper:  Yu M, Nguyen ND, Huang Y, Lin D, Fujimoto TN, Molkentine JM, Deorukhkar A, Kang Y, San Lucas FA, Fernandes CJ, Koay EJ, Gupta S, Ying H, Koong AC, Herman JM, Fleming JB, Maitra A, Taniguchi CM. Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer. JCI Insight. 2019 Jul 23;5. pii: 126915. PMID: 31335325; PMCID: PMC6777817.
doi: 10.1172/jci.insight.126915.
 

March 23, 2020
Canceled
 

April 6, 2020
Presenter:  Md Yousuf Ali
Paper: Duman C, Yaqubi K, Hoffmann A, Acikgöz AA, Korshunov A, Bendszus M, Herold-Mende C, Liu HK, Alfonso J. Acyl-CoA-Binding Protein Drives Glioblastoma Tumorigenesis by Sustaining Fatty Acid Oxidation. Cell Metab. 2019 Aug 6;30(2):274-289.e5. Epub 2019 May 2. PMID: 31056285.
doi: 10.1016/j.cmet.2019.04.004. 
Join URL: https://uiowa.zoom.us/j/934920146
 

April 20, 2020
Presenter: Dakota Thompson
Paper: Bai L, Zhou H, Xu R, Zhao Y, Chinnaswamy K, McEachern D, Chen J, Yang CY, Liu Z, Wang M, Liu L, Jiang H, Wen B, Kumar P, Meagher JL, Sun D, Stuckey JA, Wang S. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17. PMID: 31715132 PMCID: PMC6880868.
doi: 10.1016/j.ccell.2019.10.002. 
Join URL: https://uiowa.zoom.us/j/479801751
 

May 4, 2020
Presenter:  Mike Petronek
Paper: Kuang Y, Guo W, Ling J, Xu D, Liao Y, Zhao H, Du X, Wang H, Xu M, Song H, Wang T, Jing B, Li K, Hu M, Wu W, Deng J, Wang Q. Iron-dependent CDK1 activity promotes lung carcinogenesis via activation of the GP130/STAT3 signaling pathway. Cell Death Dis. 2019 Apr 1;10(4):297. PMID: 30931929; PMCID: PMC6443808. 
doi: 10.1038/s41419-019-1528-y.
Join URL: https://uiowa.zoom.us/j/198062071