Cancer Biology Journal Club, The University of Iowa
Fall 2019, 11:30-12:30, Every Other Monday, Room B180 Med Labs
Contact: douglas-spitz@uiowa.edu Tel 319/335-8019
 

August 26, 2019
Presenter: Dr. Frederick Domann
Paper: Messerli SM, Schaefer AM, Zhuang Y, Soltys BJ, Keime N, Jin J, Ma L, Hsia CJC, Miskimins WK. Use of Antimetastatic SOD3-Mimetic Albumin as a Primer in Triple Negative Breast Cancer. J Oncol. 2019 Feb 28;2019:3253696. PMID: 30941174; PMCID: PMC6420975.
doi: 10.1155/2019/3253696
 

September 9, 2019
Presenter: Michelle Tamplin
Paper: Bodo S, Campagne C, Thin TH, Higginson DS, Vargas HA, Hua G, Fuller JD, Ackerstaff E, Russell J, Zhang Z, Klingler S, Cho H, Kaag MG, Mazaheri Y, Rimner A, Manova-Todorova K, Epel B, Zatcky J, Cleary CR, Rao SS, Yamada Y, Zelefsky MJ, Halpern HJ, Koutcher JA, Cordon-Cardo C, Greco C, Haimovitz-Friedman A, Sala E, Powell SN, Kolesnick R, Fuks Z. Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury. J Clin Invest. 2019 Feb 1;129(2):786-801. PMID: 30480549; PMCID: PMC6355243.
doi: 10.1172/JCI97631
 

September 23, 2019
Presenter: Mike Petronek
Paper:Schonberg DL, Miller TE, Wu Q, Flavahan WA, Das NK, Hale JS, Hubert CG, Mack SC, Jarrar AM, Karl RT, Rosager AM, Nixon AM, Tesar PJ, Hamerlik P, Kristensen BW, Horbinski C, Connor JR, Fox PL, Lathia JD, Rich JN. Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells. Cancer Cell. 2015 Oct 12;28(4):441-455. PMID: 26461092; PMCID: PMC4646058.
doi: 10.1016/j.ccell.2015.09.002
 

October 7, 2019
Presenter: Michael Petronek
Paper: Chitambar CR, Al-Gizawiy MM, Alhajala HS, Pechman KR, Wereley JP, Wujek R, Clark PA, Kuo JS, Antholine WE, Schmainda KM. Gallium Maltolate Disrupts Tumor Iron Metabolism and Retards the Growth of Glioblastoma by Inhibiting Mitochondrial Function and Ribonucleotide Reductase. Mol Cancer Ther. 2018 Jun;17(6):1240-1250. PMID: 29592883; PMCID: PMC5984712.
doi: 10.1158/1535-7163.MCT-17-1009
 

October 21, 2019
Presenter: Dr. Ann Miller
Paper: Liu M, O'Connor RS, Trefely S, Graham K, Snyder NW, Beatty GL. Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal. Nat Immunol. 2019 Jan 21;20(3):265-275. PMID: 30664738; PMCID: PMC6380920.
doi: 10.1038/s41590-018-0292-y
 

November 4, 2019
Presenter: Collin Heer
Paper: Chowdhry S, Zanca C, Rajkumar U, Koga T, Diao Y, Raviram R, Liu F, Turner K, Yang H, Brunk E, Bi J, Furnari F, Bafna V, Ren B, Mischel PS. NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling. Nature. 2019 May;569(7757):570-575.
Epub 2019 Apr 24. PMID: 31019297.
doi: 10.1038/s41586-019-1150-2
 

November 18, 2019
Presenter:  Michael Petronek
Paper: Muir RK, Zhao N, Wei J, Wang YH, Moroz A, Huang Y, Chen YC, Sriram R, Kurhanewicz J, Ruggero D, Renslo AR, Evans MJ. Measuring Dynamic Changes in the Labile Iron Pool in Vivo with a Reactivity-Based Probe for Positron Emission Tomography. ACS Cent Sci. 2019 Apr 24;5(4):727-736. PMID: 31041393; PMCID: PMC6487455.
doi: 10.1021/acscentsci.9b00240
 

December 2, 2019
Presenter: Dr. Marion Vanneste
Paper: Giudetti AM, De Domenico S, Ragusa A, Lunetti P, Gaballo A, Franck J, Simeone P, Nicolardi G, De Nuccio F, Santino A, Capobianco L, Lanuti P, Fournier I, Salzet M, Maffia M, Vergara D. A specific lipid metabolic profile is associated with the epithelial mesenchymal transition program. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Mar;1864(3):344-357. PMID: 30578966.
doi: 10.1016/j.bbalip.2018.12.011