Spring 2009

12:00-1:00, Wednesdays

Room B180, Med Labs
Contact: garry-buettner@uiowa.edu Tel 319/335-6749

January 21, 2009
Presenter: Dr. Joshua Madsen
Paper: Rai P, Onder TT, Young JJ, McFaline JL, Pang B, Dedon PC, Weinberg RA.
(2008) Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proc Natl Acad Sci U S A. 106(1):169-174. PMID: 19118192
[DOI Article]

January 28, 2009
Presenter: Peter Nagy
Paper: Suraweera A, Becherel OJ, Chen P, Rundle N, Woods R, Nakamura J, Gatei M, Criscuolo C, Filla A, Chessa L, Fußer M, Epe B, Gueven N, Lavin M (2007) Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage. J Cell Bio 177(6): 969-979
[DOI Article]

February 4, 2009
Presenter: Dr. Garry Buettner
Paper: Townsend DM, Manevich Y, He L, Hutchens S, Pazoles CJ, Tew KD. (2008) Novel Role for Glutathione S-Transferase {pi}: REGULATOR OF PROTEIN S- GLUTATHIONYLATION FOLLOWING OXIDATIVE AND NITROSATIVE STRESS. J
Biol Chem. 284(1):436-445. PMID: 18990698, PMCID: PMC2610519
[DOI Article]

February 11, 2009
Presenter: Amanda Kalen
Paper: Houstis N, Rosen ED, Lander ES. (2006) Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature. 440(7086):944-948. PMID: 16612386
[DOI Article]

February 18, 2009
Presenter: Yueming Zhu
Paper: Itoh S, Ozumi K, Kim HW, Nakagawa O, McKinney RD, Folz RJ, Zelko IN, Ushio-Fukai M, Fukai T. (2009) Novel mechanism for regulation of extracellular SOD
transcription and activity by copper: role of antioxidant-1. Free Radic Biol Med. 46(1):95-
104. PMID: 18977292 PMCID: PMC2630370
[DOI Article]

February 25, 2009
Presenter: Dr. Prabhat Goswami
Paper: Gao X, Campian JL, Qian M, Sun XF, Eaton JW. (2009) Mitochondrial DNA
Damage in Iron Overload. J Biol Chem. 284(8):4767-4775. PMID: 19095657
[DOI Article]

March 4, 2009
Presenter: Tony Cyr
Paper: Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp
MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S.
(2008) UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals.
Nature. 454(7206):846-851. PMID: 18668043
[DOI Article]

March 11, 2009
Presenter: Dr. Nukhet Aykin-Burns
Paper: Jeney V, Komódi E, Nagy E, Zarjou A, Vercellotti GM, Eaton JW, Balla G, Balla
J. (2009) Supression of hemin-mediated oxidation of low-density lipoprotein and
subsequent endothelial reactions by hydrogen sulfide (H2S). Free Radic Biol Med.
46(5):616-623. PMID: 19100829
[DOI Article]

March 18, 2009
Presenter: No Meeting – Spring Break

March 25, 2009
Presenter: Dr. Douglas Spitz
Paper: Wood JM, Decker H, Hartmann H, Chavan B, Rokos H, Spencer JD, Hasse S,
Thornton MJ, Shalbaf M, Paus R, Schallreuter KU. (2009) Senile hair graying: H2O2-
mediated oxidative stress affects human hair color by blunting methionine sulfoxide
repair. FASEB J. [Epub ahead of print] PMID: 19237503
[DOI Article]

April 1, 2009
Presenter: Mitch Coleman
Paper: Tapryal N, Mukhopadhyay C, Das D, Fox PL, Mukhopadhyay CK. (2009)
Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism
involving its 3'-untranslated region: implications in neurodegenerative diseases. J Biol
Chem. 284(3):1873-1883. PMID: 19019832
[DOI Article]

April 8, 2009
Presenter: Maneesh Kumar
Paper: Chiribau CB, Cheng L, Cucoranu IC, Yu YS, Clempus RE, Sorescu D. (2008)
FOXO3A Regulates Peroxiredoxin III Expression in Human Cardiac Fibroblasts. J Biol
Chem. 283(13):8211-8217.
[DOI Article]

April 15, 2009
Presenter: Jordan Witmer
Paper: Telford JE, Kilbride SM, Davey GP. (2009) Complex I Is Rate-limiting for Oxygen
Consumption in the Nerve Terminal. J Biol Chem. 284(14):9109-9114.
[DOI Article]

April 22, 2009
Presenter: Venkat Venkatesha
Paper: Choi JS, Shin S, Jin YH, Yim H, Koo KT, Chun KH, Oh YT, Lee WH, Lee SK.
(2007) Cyclin-dependent protein kinase 2 activity is required for mitochondrial
translocation of Bax and disruption of mitochondrial transmembrane potential during
etoposide-induced apoptosis. Apoptosis. 12(7):1229-1241.
[DOI Article]

April 29, 2009
Presenter: Peter Scarbrough
Paper: Lam PY, Yin F, Hamilton RT, Boveris A, Cadenas E. (2009) Elevated neuronal
nitric oxide synthase expression during ageing and mitochondrial energy production.
Free Radic Res. 4:1-9.
[DOI Article]

May 6, 2009
Presenter: Jennifer Nickerson-Gass
Paper: Yamaura M, Mitsushita J, Furuta S, Kiniwa Y, Ashida A, Goto Y, Shang WH,
Kubodera M, Kato M, Takata M, Saida T, Kamata T. (2009) NADPH oxidase 4
contributes to transformation phenotype of melanoma cells by regulating G2-M cell
cycle progression. Cancer Res. 69(6):2647-54. PMID: 19276355
[DOI Article]