Lab

Spitz Lab

Select Publications

Spitz DR, Li GC, McCormick ML, Sun Y, Oberley LW.  Stable H2O2-resistant variants of Chinese hamster fibroblasts demonstrate increases in catalase activity. Rad Res; 1988; 114:114-124. PMID: 3353499

Spitz DR, Li GC, McCormick ML, Sun Y, Oberley LW.  The isolation and partial characterization of stable H2O2-resistant variants of Chinese hamster fibroblasts. In: Oxygen Radicals in Biology and Medicine (Ed. M. Simic), Plenum Press, 1988; pp. 549-552. PMID: 3250510

Oberley LW, McCormick ML, Sierra-Rivera E, Kasemeset-St.Clair D. Manganese superoxide dismutase in normal and transformed human embryonic lung fibroblasts. Free Radic Biol Med; 1989; 6:379-384. PMID: 2540070

Spitz DR, Mackey, Li GC, Elwell JH, McCormick ML, Oberley LW. Relationship between changes in ploidy and stable cellular resistance to hydrogen peroxide. J Cell Physiol; 1989; 139:592-598. PMID: 2738104

Sun Y, Peterson TE, McCormick ML, Oberley LW, Osborne JW. Improved superoxide dismutase assay for clinical use. Clin Chem; 1989; 35:1265. PMID: 2731356

Claycamp HG, McCormick ML, DeRose CM, Elwell JH, Oberley LW.  Superoxide dismutase and media dependence of far-uv radiation resistance in thiol-treated cells. Intl J Rad Biol., 1990; 58:449-461. PMID: 1975607

McCormick ML, Oberley TD, Elwell JH, Oberley LW, Sun Y, Li JJ. Superoxide dismutase and catalase levels during estrogen-induced renal tumorigenesis, in renal tumors and their autonomous variants in the Syrian hamster. Carcinogenesis. 1991; 12(6):977-983. PMID: 2044204

McCormick ML, Oberley LW, Oberley TD, Britigan BE. Manganese superoxide dismutase is associated with the neutrophil plasma membrane. In: Proceedings of the MSU/Keystone Symposium on the Molecular Basis of Oxidative Damage by Leukocytes. CRC Press, Boca Raton, FL 1991; pp. 317-320.

Britigan BE, Roeder TL, Rasmussen GT, Shasby DM, McCormick ML, Cox CD. Interaction of the Pseudomonas aeruginosa secretory products pyocyanin and pyochelin results in the generation of hydroxyl radical. Implications for pseudomonas-associated tissue injury. J Clin Invest; 1992; 90:2187-2196. PMID: 1469082, PMCID: PMC443369.

McCormick ML, Railsback MA, Roeder TL, Britigan BE. Eosinophil peroxidase-dependent hydroxyl radical formation by human eosinophils. J Biol Chem. 1994: 269:27914-27919. PMID: 7961724

Oberley TD, Sempf JM, Oberley MJ, McCormick ML, Muse KE, Oberley LW. Immunogold analysis of antioxidant enzymes in human renal carcinoma. Virchows Arch Int J Pathol; 1994; 424:155-164. PMID: 8180777

McCormick ML, Buettner GR, Britigan BE.  The spin trap 4-POBN stimulates peroxidase-mediated oxidation of deferroximine: implications for pharmacological use of spin trapping agents. J Biol Chem. 1995; 270:29265-29269. PMID: 7493957

McCormick ML, Metwali A, Railsback MA, Weinstock JV, Britigan BE.  Eosinophils from schistosome-induced hepatic granulomas produce superoxide and hydroxyl radical. J Immunol; 1996; 157:5009-5015. PMID: 8943408

McCormick ML, Wilson ME, Lewis TS, Vorhies RW, Britigan BE.  Specific binding of ferrilactoferrin and ferritransferrin in the protozoan Leishmania chagasi. In: Lactoferrin: Interactions and Biological Functions (Eds. T.W. Hutchins and B. Lonerdahl), Humana Press, Totowa, NJ. 1997; pp333-342.

Britigan BE, Lewis TS, Olakanmi O, McCormick ML, Miller RA. The impact of phagocyte-lactoferrin interactions on inflammation. In: Lactoferrin: Interactions and Biological Functions (Eds. T.W. Hutchins and B. Lonerdahl), Humana Press, Totowa, NJ. 1997; pp 211-232.

Andres B, Rakasz E, Hagen M, McCormick ML, Mueller AL, Sandor BE, Britigan BE, Elliot D, Metwali A, Weinstock JV, Lynch RG. Lack of Fc-e receptors on murine eosinophils. Implications for the functional significance of elevated IgE and eosinophils in parasitic infections. Blood. 1997; 89:3826-3836. 

McCormick ML, Buettner GR, Britigan BE. Endogenous superoxide dismutase levels regulate iron-dependent hydroxyl radical formation in Escherichia coli exposed to hydrogen peroxide. J Bacteriol. 1998; 180:622-625. PMID: 9457866, PMCID: PMC106930

McCormick ML, Gaut JP, Lin T.-S., Britigan BE, Buettner GR, Heinecke JW.  Electron paramagnetic resonance detection of free tyrosyl radical generated by myeloperoxidase, lactoperoxidase, and horseradish peroxidase.  J Biol Chem. 1998; 273:32030-32037. PMID: 9822676

Britigan BE, Lewis TS, McCormick ML, Wilson ME. Evidence for the existence of a surface receptor for ferrilactoferrin and ferritransferrin associated with the plasma membrane of the protozoan parasite Leishmania donovani. Adv Exp Med Biol., 1998; 443:135-40. PMID: 9781352

Kinter M, Wolstenholme JT, Thornhill BA, Newton EA, McCormick ML, Chevalier RL. Unilateral uretreal obstruction impairs renal antioxidant enzyme activation during sodium depletion. Kidney Int. 1999; 55(4):1327-34. PMID: 10200997

McCormick ML, Denning GM, Reszka KJ, Bilski P, Buettner GR, Rasmussen GT, Railsback MA, Britigan BE. Biological effects of menadione photochemistry: effects of menadione on biological systems may not involve classical oxidant production. Biochem J. 2000; 350 Pt 3:797-804. PMID: 10970795

Henderson JP, Byun J, Williams MV, McCormick ML, Parks W, Ridnour L, Heinecke JW.  Bromination of deoxycytidine by eosinophil peroxidase: a mechanism for mutagenesis by oxidative damage of nucleotide precursors. Proc Natl Acad Sci., 2001; 98:1631-1636. PMID: 11172002, PMCID: PMC29308

Henderson JP, Byun J, Williams MV, Mueller DM, McCormick ML, Heinecke JW. Production of brominating intermediates by myeloperoxidase: a transhalogenation pathway for generating mutagenic nucleobases during inflammation. J Biol Chem., 2001; 276:7867-75. PMID: 11096071

Gantt KR, Goldman TL, McCormick ML, Miller MA, Jeronimo SMB, Nascimento ET, Britigan BE, Wilson ME. Oxidative responses of human and murine macrophages during phagocytosis of Leishmania chagasi. J Immunol., 2001; 167:893-901. PMID: 11441096

Britigan BE, Lewis TS, Waldschmidt M, McCormick ML, Krieg AM. Lactoferrin binds to and inhibits the immunostimulatory effects of CpG-containing oligonucleotides on human B cells. J Immunol., 2001; 167:2921-8. PMID: 11509640

Britigan BE, Miller RA, Hassett DJ, Pfaller MA, McCormick ML, Rasmussen GT. Antioxidant enzyme expression in clinical isolates of Pseudomonas aeruginosa: identification of an atypical form of manganese superoxide dismutase. Infect Immun., 2001; 69:7396-7401, 2001. PMID: 11705913, PMCID: PMC98827

Reszka KJ, McCormick ML, Britigan BE. Peroxidase- and nitrite-dependent metabolism of anthracycline anticancer agents daunorubicin and doxorubicin.  Biochemistry. 2001; 40:15349-61. PMID: 11735418

Wilson ME, Lewis TS, Miller MA, McCormick ML, Britigan BE.  Leishmania chagasi: uptake of iron bound to lactoferrin or transferrin requires an iron reductase. Exp Parasitol., 2002; 100:196-207.

Wagner BA, Britigan BE, Reszka KJ, McCormick ML, Burns CP. Hydrogen peroxide-induced apoptosis of HL-60 human leukemia cells is mediated by the oxidants hypochlorous acid and chloramines. Arch Biochem Biophys., 2002; 401:223-34. PMID: 12054473

O’Malley YQ, Abdalla MY, McCormick ML, Reszka KJ, Denning GM, Britigan BE. Subcellular localization of Pseudomonas pyocyanin cytotoxicity in human lung epithelial cells. Am J Physiol (Lung Cell Mol Physiol)., 2003; 284:L420-30. PMID: 12414438

Reszka KJ, McCormick ML, Britigan BE. Oxidation of anthracycline anticancer agents by the peroxidase mimic microperoxidase 11 and hydrogen peroxide. Free Radic Biol Med., 2003; 35:78-93, 2003. PMID: 12826258

Wen F, Abdalla MY, Aloman C, Xiang J, Ahmad IM, Walewski J, McCormick ML, Brown KE, Branch AD, Spitz DR, Britigan BE, Schmidt WN. Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1. J Med Virol., 2004; 72(2):230-40. PMID: 14695664

Wagner BA, Reszka KJ, McCormick ML, Britigan BE, Evig CB, Burns CP. Role of thiocyanate, bromide and hypobromous acid in hydrogen peroxide-induced apoptosis. Free Rad Res., 2004; 38:167-175. PMID: 15104210

Li WG, Gavrila D, Liu X, Wang L, Gunnlaugsson S, Stoll LL, McCormick ML, Sigmund CD, Tang C, Weintraub NL. Ghrelin inhibits proinflammatory responses and nuclear factor kB activation in human endothelial cells. Circulation, 2004, 109:2221-2226. PMID: 15117840

Reszka KJ, O'Malley Y, McCormick ML, Denning GM, Britigan BE. Oxidation of pyocyanin, a cytotoxic product from Pseudomonas aeruginosa, by microperoxidase 11 and hydrogen peroxide.  Free Radic Biol Med., 2004; 36:1448-1459. PMID: 15135182

Abdalla MY, Britigan BE, Wen F, Icardi M, McCormick ML, LaBrecque DR, Voigt M, Brown KE, Schmidt WN. Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein. J Infect Dis., 2004; 190(6):1109-1118. PMID: 15319861

Stoll LL, McCormick ML, Denning GM, Weintraub NL. Antioxidant effects of statins. Drugs Today (Barc.), 2004; 40(12):975-990. (Review). PMID: 15645009

Emerson DK, McCormick ML, Schmidt JA, Knudson CM.  Taurine monochloramine activates a cell death pathway involving Bax and caspase-9. J Biol Chem., 2005; 280(5):3233-3241. PMID: 15545281

Gavrila D, Li WG, McCormick ML, Thomas M, Daugherty A, Cassis LA, Miller FJ, Oberley LW, Dellsperger KC, Weintraub NL. Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol., 2005; 25(8):1671-7. PMID: 15933246

Thomas M, McCormick ML, Gavrila D, Miller FJ, Daugherty A, Cassis LA, Dellsperger KC, Weintraub NL. Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Circulation, 2006; 114(5):404-13. PMID: 16864727

Reszka KJ, McCormick ML, Buettner GR, Hart CM, Britigan BE.  Nitric oxide decreases the stability of DMPO spin adducts. Nitric Oxide, 2006; 15(2):133-41. PMID: 16647868

McCormick ML, Gavrila D, Weintraub NL. Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol., 2007; 27(3):461-9. (Review). PMID: 17218601