CURRENT TOPICS IN RADIATION AND CANCER BIOLOGY (77:548)

The University of Iowa

Spring 2012

11:30-12:30, Mondays

Room B180, Med Labs

Contact: apollina-goel@uiowa.edu Tel 319-384-4754

Presentations for Season 2012:

April 16, 2012
Presenter: Kelley Salem
Paper: : Jaramillo MC, Briehl MM, Crapo JD, Batinic-Haberle I, Tome ME. Manganese Porphyrin, MnTE-2-PyP(5+), Acts as a Pro-Oxidant to Potentiate Glucocorticoid-Induced Apoptosis in Lymphoma Cells. Free Radic Biol Med. 2012 Apr 15; 52(8):1272-84. Epub 2012 Feb 11. PMID:22330065

April 30, 2012
Presenter: Dr. Douglas Spitz
Paper: Paper: Ranzato E, Biffo S, and Burlando B. Selective Ascorbate Toxicity in Malignant Mesothelioma A Redox Trojan Mechanism. Am J Respir Cell Mol Biol. 2011 Jan; 44(1):108-17. PMID: 20203294

January 23, 2012
Presenter: Adam Case
Paper: Memmott RM, Mercado JR, Maier CR, Kawabata S, Fox SD, Dennis PA. Metformin prevents tobacco carcinogen-induced lung tumorigenesis. Cancer Prev Res (Phila). 2010 Sep; 3(9):1066-76. Epub 2010 Sep 1. PMCID: PMC3192328 NIHMSID: NIHMS209213

February 6, 2012
Presenter: Cameron Cushing
Paper: Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat Med. 2011 Oct 30; 17(11):1498-503. PMID:22037646

February 20, 2012
Presenter: James Jacobus
Paper: Masgras I, Carrera S, de Verdier PJ, Brennan P, Majid A, Makhtar W, Tulchinksy E, Jones GD, Roninson IB, Macip S. Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21. J Biol Chem. 2012 Feb 6. [Epub ahead of print] PMID: 22311974

March 5, 2012
Presenter: Elise Fletcher
Paper: Singh A, Sweeney MF, Yu M, Burger A, Greninger P, Benes C, Haber DA, Settleman J. TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers. Cell. 2012 Feb 17; 148(4):639-50. PMID:22341439

March 19, 2012
Presenter: Lauren Wegman
Paper: Yang W-H, Lan H-Y, Huang C-H, Tai S-K, Tzeng C-H, Kao S-Y, Wu K-J, Hung M-C, and Yang M-H. RAC1 activation mediates Twist1-induced cancer cell migration. Nature Cell Biology, published online 11 March 2012.

April 2, 2012
Presenter: John Lehn
Paper: Ham SA, Hwang JS, Yoo T, Lee H, Kang ES, Park C, Oh JW, Lee HT, Min G, Kim JH, Seo HG. Ligand-activated PPARδ inhibits ultraviolet B-induced senescence of human keratinocytes via PTEN-mediated inhibition of superoxide production. Biochem J. 2012 Feb 16. [Epub ahead of print]