Free Radical Journal Club, The University of Iowa
Fall 2016, 11:30-12:30, Mondays, Room B180, Med Labs
Contact: garry-buettner@uiowa.edu Tel 319/335-8015

August 22, 2016
Presenter: Paige Kluz
Paper: Dong K, Ni H, Wu M, Tang Z, Halim M, Shi D. ROS-mediated glucose metabolic reprogram induces insulin resistance in type 2 diabetes. Biochem Biophys Res Commun. 2016 Aug 5;476(4):204-11.
doi: 10.1016/j.bbrc.2016.05.087. PMID: 27207834.

September 5, 2016
Presenter: No FRJC, Labor Day

September 19, 2016
Presenter: Shane Solst
Paper: Hanzén S, Vielfort K, Yang J, Roger F, Andersson V, Zamarbide-Forés S, Andersson R, Malm L, Palais G, Biteau B, Liu B, Toledano MB, Molin M, Nyström T. Lifespan Control by Redox-Dependent Recruitment of Chaperones to Misfolded Proteins. Cell. 2016 Jun 30;166(1):140-51. PMID:27264606.
doi: 10.1016/j.cell.2016.05.006

October 3, 2016
Presenter: Adrienne Klinger
Paper:  Krick S, Wang J, St-Pierre M, Gonzalez C, Dahl G, Salathe M. Dual Oxidase 2 (Duox2) Regulates Pannexin 1-mediated ATP Release in Primary Human Airway Epithelial Cells via Changes in Intracellular pH and Not H2O2 Production. J Biol Chem. 2016 Mar 18;291(12):6423-32. PMID: 26823467 PMCID: PMC4813552.
doi: 10.1074/jbc.M115.664854.

October 17, 2016
Presenter: Collin Heer
Paper: Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, Stockwell BR. Regulation of ferroptotic cancer cell death by GPX4. Cell. 2014 Jan 16;156(1-2):317-31. PMID: 24439385; PMCID: PMC4076414.
doi: 10.1016/j.cell.2013.12.010.

October 31, 2016
Presenter: Kelly Falls
Paper: Sada K, Nishikawa T, Kukidome D, Yoshinaga T, Kajihara N, Sonoda K, Senokuchi T, Motoshima H, Matsumura T, Araki E. Hyperglycemia Induces Cellular Hypoxia
through Production of Mitochondrial ROS Followed by Suppression of Aquaporin-1. PLoS One. 2016 Jul 6;11(7):e0158619. PMID: 27383386; PMCID: PMC4934928.
doi: 10.1371/journal.pone.0158619

November 14, 2016
Presenter: Paul Akhenblit
Paper: Marin JJ, Lozano E, Perez MJ. Lack of mitochondrial DNA impairs chemical hypoxia-induced autophagy in liver tumor cells through ROS-AMPK-ULK1 signaling dysregulation independently of HIF-1α.
Free Radic Biol Med. 2016 Sep 26;101:71-84. PMID: 27687210.
doi: 10.1016/j.freeradbiomed.2016.09.025.

November 28, 2016
Presenter: Jessica Reedy
Paper: Böhm B, Heinzelmann S, Motz M, Bauer G. Extracellular localization of catalase is associated with the transformed state of malignant cells. Biol Chem. 2015 Dec;396(12):1339-56. PMID: 26140730.
doi: 10.1515/hsz-2014-0234.