Welcome

The Free Radical and Radiation Biology Program (FRRBP) is a unique, storied PhD-granting program that resides within the Department of Radiation Oncology at the University of Iowa Carver College of Medicine. FRRBP provides graduate students the opportunity to study cancer biology and other major human diseases through a unique curriculum developed to advance redox biology through translational biomedical research and vice versa. This curriculum was developed through foundational studies of free radical and radiation biology within a research setting as close to clinical care as possible. We are the only PhD graduate program within a clinical department in the USA, providing students a more balanced education for biomedical research and the chance to directly implement your research for cancer therapy and therapy development.  Our program is affiliated with researchers in cancer, heart disease, arthritis, wound healing, fibrosis, diabetes, cystic fibrosis and several clinical trials for redox related compounds.  We have two $10M program grants affiliated with our groups and are a national leader in cancer research. 

About us

The FRRBP program is one of 7 Biomedical Science programs offered through the College of Liberal Arts and Sciences staffed by 8 primary and 21 secondary faculty with exposure to related fields. 

What is FRRBP?

Aging and Cancer | Radiation Induced Normal Tissue Injury 
Inflammation and Arthritis | Cardiovascular diseases
Immunological responses | Toxicology in Cancer Therapy
Neuro Oncology | Basic and Translational Cancer Research

Research Focus

  • Fundamental free radical, oxidant and antioxidant chemistry and biology;
  • Basics of redox biology;
  • The biology of cancer including the biological mechanisms of anticancer therapy, as well as the mechanisms of normal tissue damage during cancer therapy
  • The redox and free radical biology of disease.

Program requirements

Two programs are offered:
1-Graduate Program in Free Radical and Radiation Biology, Ph.D. Objective

FRRPB is an interdisciplinary graduate program that provides students with a fundamental grounding in Free Radical Biology and Radiation Biology. All students devise an individualized program to apply the basics of free radical biology to their research program on the fundamental mechanisms and treatment of disease.

2-Postdoctoral Program in Free Radical and Radiation Biology:
FRRBP has a formal, NIH grant supported Training Program for Postdoctoral Scholars. 
The FRRBP is involved in three major activities related to radiation, free radical, and cancer biology at The University of Iowa; these are:
Teaching: involves the organization and presentation of courses within the FRRB Program and other graduate and undergraduate courses, teaching radiation biology to residents in Radiation Oncology and Diagnostic Radiology, to fourth year medical students, and to Nuclear Medicine and X-ray technologists.

Research: in the FRRB Program is investigating the fundamental biology of free radicals and related oxidants and antioxidants in health and disease. This includes, the role of these species in proliferative diseases, such as cancer; antitumor therapy; radiation-induced alterations in gene expression; redox regulation of transcription factor activation, oncogenes and suppressor genes; carcinogenesis; gene therapy; epigenetic effects; pathogenesis of radiation-induced normal tissue injury; cell population kinetics in normal and malignant tissues.  

Service: involves contributing to administration within the University and guiding the structure and evolution of science in the U.S. and beyond.

Apply:

E-mail | Toll-free at (866) 448-4610 

Thank you for your interest in the Free Radical and Radiation Biology Graduate Program. The Biomedical Science Program (BSP) oversees admissions and first-year graduate studies for 7 doctoral programs, including Free Radical and Radiation Biology.

Faculty

FRRBP Primary Faculty

Primary faculty in the Division of Free Radical and Radiation Biology.

 

News

Madeline Hines SfRBM winner
Madeline Hines is one of two top-scored abstracts for this year's SfRBM Young Investigator Award. She scooped the Irwin Fridovich YIA Award at the 2021 virtual conference with her abstract titled "Lipid Peroxidation Regulates Chondrocyte Mitochondrial Dynamics and Cartilage Injury Response".
Sarita Menon, a graduate student from the FRRBP program, was the featured scientist on the University of Iowa's Graduate College page. Dr Menon graduated the program in 2006 under the mentorship of Prabhat Goswami and is noted for her passion to interest girls (and boys) in STEM related careers.
Image of Jayden Bisson and poster
Two FRRBP students performed admirably at the annual student research day hosted by the College of Medicine on September 16, 2021
Portrait of Daret St Clair and Mekhla
Daret St. Clair received an "Award for Achievement" at a ceremony hosted by the Carver College of Medicine, at the Coralville Hyatt, on September 17 to recognize her contribution to the fields of redox biology, cancer research and therapy. Introduced by Mekhla Singhania, a student in the FRRBP, where Dr St. Clair was once herself a student.