Spring 2016, 11:30-12:30, Mondays, Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

January 25, 2016
Presenter: Dr. Ehab Sarsour
Paper: Jiang Y, Pan Y, Rhea PR, Tan L, Gagea M, Cohen L, Fischer SM, Yang P. A Sucrose-Enriched Diet Promotes Tumorigenesis in Mammary Gland in Part through the 12-Lipoxygenase Pathway. Cancer Res. 2016 Jan 1;76(1):24-9.
PMID: 26729790; PMCID: PMC4703949.
doi: 10.1158/0008-5472.CAN-14-3432.

February 8, 2016
Presenter: John Lafin
Paper: De Henau S, Tilleman L, Vangheel M, Luyckx E, Trashin S, Pauwels M, Germani F, Vlaeminck C, Vanfleteren JR, Bert W, Pesce A, Nardini M, Bolognesi M, De Wael K, Moens L, Dewilde S, Braeckman BP. A redox signalling globin is essential for reproduction in Caenorhabditis elegans. Nat Commun. 2015 Dec 1;6:8782. PMID: 26621324; PMCID: PMC4686822. doi: 10.1038/ncomms9782.

February 22, 2016
Presenter: Cameron Cushing
Paper: Kuiper C, Vissers MC, Hicks KO. Pharmacokinetic modeling of ascorbate diffusion through normal and tumor tissue. Free Radic Biol Med. 2014 Dec;77:340-52. PMID: 25277418 doi: 10.1016/j.freeradbiomed.2014.09.023.

March 7, 2016
Presenter: Paige Kluz
Paper: Shin JA, Yoon JC, Kim M, Park EM. Activation of classical estrogen receptor subtypes reduces tight junction disruption of brain endothelial cells under ischemia/reperfusion injury. Free Radic Biol Med. 2016 Mar;92:78-89. PMID: 26784014.
doi: 10.1016/j.freeradbiomed.2016.01.010.

March 21 2016
Presenter: Adrienne Klinger
Paper: Chang CY, Chen JY, Chen SH, Cheng TJ, Lin MT, Hu ML. Therapeutic treatment with ascorbate rescues mice from heat stroke-induced death by attenuating systemic inflammatory response and hypothalamic neuronal damage. Free Radic Biol Med. 2016 Apr; 93:84-93. PMID: 26703968.
doi: 10.1016/j.freeradbiomed.2015.12.017.

April 4, 2016
Presenter: Shane Solst
Paper: Wang L, Sun Q, Wang X, Wen T, Yin JJ, Wang P, Bai R, Zhang XQ, Zhang LH, Lu AH, Chen C. Using hollow carbon nanospheres as a light-induced free radical generator to overcome chemotherapy resistance. J Am Chem Soc. 2015 Feb 11;137(5):1947-55. PMID: 25597855.
doi: 10.1021/ja511560b.

April 18, 2016
Presenter: Kelly Falls
Paper: Kelly Falls
Paper:  Kerr EM, Gaude E, Turrell FK, Frezza C, Martins CP. Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities. Nature. 2016 Mar 3;531(7592):110-3. PMID: 26909577; PMCID: PMC4780242.
doi: 10.1038/nature16967.

May 2, 2016
Presenter: Josh Schoenfeld
Paper: Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM. Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Nat Med. 2016 Jan 11. PMID: 26752519. doi: 10.1038/nm.4021.