Fall 2014, 11:30-12:30, Mondays, Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

August 25, 2014
Presenter: Douglas R. Spitz
Paper: Sayin VI, Ibrahim MX, Larsson E, Nilsson JA, Lindahl P, Bergo MO. Antioxidants accelerate lung cancer progression in mice. Sci Transl Med. 2014 Jan 29;6(221):221ra15. [DOI Link, http://dx.doi.org/doi:10.1126/scitranslmed.3007653].

September 8, 2014
Presenter: John Cieslak
Paper: Revsbech IG, Shen X, Chakravarti R, Jensen FB, Thierl B, Evans Al, Kindberg J, Frobert O, Stuehr DJ, Kevil CG, Fago A. Hydrogen sulfide and nitric oxide metabolites in the blood of free-ranging brown bears and their potential roles in hibernation. Free Radic Biol Med. 2014 Aug;73:349-57. [DOI Link, http://dx.doi.org/doi:10.1016/j.freeradbiomed.2014.05.025].

Sept 22, 2014
Presenter: Cameron Cushing
Paper: Al-Qenaei A, Yiakouvaki A, Reelfs O, Santambrogio P, Levi S, Hall ND, Tyrrell RM, Pourzand C. Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide. Free Radic Biol Med. 2014;68:87-100.
[DOI Link, http://dx.doi.org/doi:10.1016/j.freeradbiomed.2013].

October 6, 2014
Presenter: Somya Kapoor 
Paper:  Algire C, Moiseeva O, Deschênes-Simard X, Amrein L, Petruccelli L, Birman E, Viollet B, Ferbeyre G, Pollak MN. Metformin reduces endogenous reactive oxygen species and associated DNA damage. Cancer Prev Res (Phila). 2012 Apr;5(4):536-43.
[DOI Link, http://dx.doi.org/doi:10.1158/1940-6207.CAPR-11-0536].

October 20, 2014
Presenter: Jyungmean Son
Paper: Sing A, Tsatskis Y, Fabian L, Hester I, Rosenfeld R, Serricchio M, Yau N, Bietenhader M, Shanbhag R, Jurisicova A, Brill JA, McQuibban GA, McNeill H. The atypical cadherin fat directly regulates mitochondrial function and metabolic state. Cell. 2014 Sep 11;158(6):1293-308. doi: 10.1016/j.cell.2014.07.036.
[DOI Link, http://dx.doi.org/doi:10.1016/j.cell.2014.07.036].

November 3, 2014
Presenter: Jenna Casey
Paper: Jarman ER, Khambata VS, Cope C, Jones P, Roger J, Ye LY, Duggan N, Head D, Pearce A, Press NJ, Bellenie B, Sohal B, Jarai G. n inhibitor of NADPH oxidase-4 attenuates established pulmonary fibrosis in a rodent disease model. Am J Respir Cell Mol Biol. 2014 Jan;50(1):158-69. PMID: 23977848.
[DOI Link, http://dx.doi.org/doi:10.1165/rcmb.2013-0174OC].

November 17, 2014
Presenter: John Lafin
Paper: Dias IH, Mistry J, Fell S, Reis A, Spickett CM, Polidori MC, Lip GY, Griffiths HR. Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation. Free Radic Biol Med. 2014; 75:49-59.
[DOI Link, doi: 10.1016/j.freeradbiomed.2014.07.012.].

December 1, 2014
Presenter: Madelyn Espinosa-Cotton
Paper: Nisimoto Y, Diebold BA, Constentino-Gomes D, Lambeth JD. Nox4: a hydrogen peroxide-generating oxygen sensor. Biochemistry. 2014 Aug 12;53(31):5111-20. PMCID: PMC4131900.
[DOI Link, http://dx.doi.org/doi:10.1021/bi500331y].