This describes the program focus on redox metabolism, in particular the wide range of cellular mechanisms that it involves
The Free Radical and Radiation Biology Program has been around since 1947. It is a PhD program that trains both predoctoral and postdoctoral students in redox biology, free radical and cancer research. All our faculty are passionate about their chosen fields as well as being committed to their research, training, and mentoring of the next generation of scientists in the field.
The University of Iowa is a major national research university located on a beautiful 1,900-acre campus in Iowa City in southeast Iowa, on the Iowa River. Our program has offices and labs located on the west side of campus in two buildings: B180 Medical Laboratories (ML) and in the Medical Education and Biomedical Research Facility (MERF).
We offer two programs:
1-Graduate Program in Free Radical and Radiation Biology, Ph.D. Objective
The Free Radical and Radiation Biology Program is an interdisciplinary graduate program that provides students with a fundamental grounding in Free Radical Biology and Radiation Biology. All students devise an individualized program to apply the basics of free radical biology to their research program on the fundamental mechanisms and treatment of disease. Many students direct their scholarly activities to research on some aspect of cancer. However, students have elected to focus on a wide range of human disease. Some examples are cardiovascular disease, diabetes, human toxicology, environmental science, and immunology/infectious disease. Our goal is to educate the next generation of leaders in the student’s chosen field.
2-Postdoctoral Program in Free Radical and Radiation Biology:
The Free Radical and Radiation Biology Program has a formal Training Program for Postdoctoral Scholars. This program is supported by an NIH Training grant as well as individual research grants of faculty in the Program.
What does the Free Radical and Radiation Biology Program do?
The FRRBP is involved in three major activities related to radiation, free radical, and cancer biology at The University of Iowa; these are:
- Research and
Teaching:involves the organization and presentation of courses within the FRRB Program and other graduate and undergraduate courses, teaching radiation biology to residents in Radiation Oncology and Diagnostic Radiology, to fourth year medical students, and to Nuclear Medicine and X-ray technologists.
Research: in the FRRB Program is investigating the fundamental biology of free radicals and related oxidants and antioxidants in health and disease. This includes, the role of these species in proliferative diseases, such as cancer; antitumor therapy; radiation-induced alterations in gene expression; redox regulation of transcription factor activation, oncogenes and suppressor genes; carcinogenesis; gene therapy; epigenetic effects; pathogenesis of radiation-induced normal tissue injury; cell population kinetics in normal and malignant tissues. All of these efforts are grounded to fundamental studies on the chemistry and biochemistry of free radicals and antioxidants.
Service: involves contributing to administration within the University and guiding the structure and evolution of science in the U.S. and beyond.