The Radiation and Free Radical Research Core (RFRRC) provides state-of-the-art technologies to investigators studying oxidative stress and redox biology as they relate to cancer biology, cancer therapy, and degenerative diseases of aging. The RFRRC offers easy access to free radical and radiation biology expertise, reagents, technologies, and analysis for researchers conducting basic, pre-clinical, and clinical studies — at the University of Iowa and beyond.
LEADERSHIP
Core Director: Douglas Spitz, PhD
IRS Co-Director: Michael Petronek, PhD
ESR Co-Director: Garry Buettner, PhD
AES Co-Director: Douglas Spitz, PhD
Electron Spin Resonance (ESR)
Offers ESR services and other detection methodologies for measuring free radicals, singlet oxygen, nitric oxide, and a range of related oxidants and oxidative damage products.
Hours: Monday–Friday, 8 AM–5 PM
Extended hours available upon request.
Contact: Brett Wagner — brett-wagner@uiowa.edu
Antioxidant Enzyme Services (AES)
Provides access to technologies for modifying and measuring molecules involved in pro-oxidant formation, reactive oxygen species metabolism, and redox biology — including antioxidant proteins and enzymes, small molecular weight cellular thiols and reductants, and redox-mediated signaling and gene expression pathways.
Hours: Monday–Friday, 8 AM–5 PM
Extended hours available upon request.
Contact: Douglas Spitz — douglas-spitz@uiowa.edu
Ionizing Radiation Services (IRS)
Provides research-related radiation treatments for eukaryotic and prokaryotic cells, viruses, small animals, and non-biological materials.
Hours: Monday–Friday, 8 AM–5 PM
Special arrangements available upon request.
Contact: radcore@uiowa.edu