Carver College of Medicine profile

Selected Publications

• Won, W. J., Deshane, J. S., Leavenworth, J. W., Oliva, C. R. & Griguer, C. E. (2019). Metabolic and functional reprogramming of myeloid-derived suppressor cells and their therapeutic control in glioblastoma. Cell stress 3 (2) 47-65. PMID: 31225500. DOI: 10.15698/cst2019.02.176.
• Oliva, C. R., Halloran, B., Hjelmeland, A. B., Vazquez, A., Bailey, S. M., Sarkaria, J. N. & Griguer, C. E. (2018). IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling. Cell communication and signaling : CCS 16 (1) 61. PMID: 30231881. DOI: 10.1186/s12964-018-0273-7.
• Oliva, C. R., Zhang, W., Langford, C., Suto, M. J. & Griguer, C. E. (2017). Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit. Oncotarget 8 (23) 37568-37583. PMID: 28455961. DOI: 10.18632/oncotarget.17247.
• Oliva, C. R., Markert, T., Ross, L. J., White, E. L., Rasmussen, L., Zhang, W., Everts, M., Moellering, D. R., Bailey, S. M., Suto, M. J. & Griguer, C. E. (2016). Identification of Small Molecule Inhibitors of Human Cytochrome c Oxidase That Target Chemoresistant Glioma Cells. The Journal of biological chemistry 291 (46) 24188-24199. PMID: 27679486. DOI: 10.1074/jbc.M116.749978.
• King, A. L., Mantena, S. K., Andringa, K. K., Millender-Swain, T., Dunham-Snary, K. J., Oliva, C. R., Griguer, C. E. & Bailey, S. M. (2016). The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease. Redox biology 9 188-197. PMID: 27566282. DOI: 10.1016/j.redox.2016.08.005.
• Oliva, C. R., Markert, T., Gillespie, G. Y. & Griguer, C. E. (2015). Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomas. Oncotarget 6 (6) 4330-44. PMID: 25726526. DOI: 10.18632/oncotarget.3015.
• Oliva, C. R., Moellering, D. R., Gillespie, G. Y. & Griguer, C. E. (2011). Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production. PloS one 6 (9) e24665. PMID: 21931801. DOI: 10.1371/journal.pone.0024665.
• Griguer, C. E. & Oliva, C. R. (2011). Bioenergetics pathways and therapeutic resistance in gliomas: emerging role of mitochondria. Current pharmaceutical design 17 (23) 2421-7. PMID: 21827418. DOI: 10.2174/138161211797249251.
• Oliva, C. R., Nozell, S. E., Diers, A., McClugage, 3rd, S. G., Sarkaria, J. N., Markert, J. M., Darley-Usmar, V. M., Bailey, S. M., Gillespie, G. Y., Landar, A. & Griguer, C. E. (2010). Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. The Journal of biological chemistry 285 (51) 39759-67. PMID: 20870728. DOI: 10.1074/jbc.M110.147504.
• Oliva, C. R., Swiecki, M. K., Griguer, C. E., Lisanby, M. W., Bullard, D. C., Turnbough, Jr, C. L. & Kearney, J. F. (2008). The integrin Mac-1 (CR3) mediates internalization and directs Bacillus anthracis spores into professional phagocytes. Proceedings of the National Academy of Sciences of the United States of America 105 (4) 1261-6. PMID: 18216258. DOI: 10.1073/pnas.0709321105.