Frederick Domann, PhD

Emeritus Professor

Example Publications

Google Scholar | Pubmed

  1. Cyr AR, Kulak MV, Park JM, Bogachek MV, Spanheimer PM, Woodfield GW,
    White-Baer LS, O'Malley YQ, Sugg SL, Olivier AK, Zhang W, Domann FE, Weigel RJ.
    TFAP2C governs the luminal epithelial phenotype in mammary development and
    carcinogenesis. Oncogene. 2014 Jan 27. doi: 10.1038/onc.2013.569. [Epub ahead of
    print] PubMed PMID: 24469049.
  2. Case AJ, Domann FE. Absence of manganese superoxide dismutase delays
    p53-induced tumor formation. Redox Biol. 2014 Jan 13;2:220-3. doi:
    10.1016/j.redox.2014.01.001. eCollection 2014. PubMed PMID: 24494196; PubMed
    Central PMCID: PMC3909777.
  3. Place TL, Nauseef JT, Peterson MK, Henry MD, Mezhir JJ, Domann FE.
    Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during
    epithelial-to-mesenchymal transition. PLoS One. 2013 Dec 18;8(12):e83021. doi:
    10.1371/journal.pone.0083021. eCollection 2013. PubMed PMID: 24367580; PubMed
    Central PMCID: PMC3867438.
  4. Vorrink SU, Severson PL, Kulak MV, Futscher BW, Domann FE. Hypoxia perturbs
    aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in
    human skin and liver-derived cell lines. Toxicol Appl Pharmacol. 2014 Feb
    1;274(3):408-16. doi: 10.1016/j.taap.2013.12.002. Epub 2013 Dec 16. PubMed PMID:
    24355420; PubMed Central PMCID: PMC3919493.
  5. Teoh-Fitzgerald ML, Fitzgerald MP, Zhong W, Askeland RW, Domann FE. Epigenetic
    reprogramming governs EcSOD expression during human mammary epithelial cell
    differentiation, tumorigenesis and metastasis. Oncogene. 2014 Jan
    16;33(3):358-68. doi: 10.1038/onc.2012.582. Epub 2013 Jan 14. PubMed PMID:
    23318435; PubMed Central PMCID: PMC3711965.
  6. Case AJ, Madsen JM, Motto DG, Meyerholz DK, Domann FE. Manganese superoxide
    dismutase depletion in murine hematopoietic stem cells perturbs iron homeostasis,
    globin switching, and epigenetic control in erythrocyte precursor cells. Free
    Radic Biol Med. 2013 Mar;56:17-27. doi: 10.1016/j.freeradbiomed.2012.11.018. Epub
    2012 Dec 5. PubMed PMID: 23219873; PubMed Central PMCID: PMC3578015

Honors, Awards and Memberships

  • 2011 Radiation Research Society -Distinguished Alumnus of the University of Wisconsin Platteville.
  • 1997 Radiation Research Society Travel Award (Yuanhui Huang)
  • 1996 Presidential Young Investigator Award, The Oxygen Society (Yuanhui Huang)
  • 1996 Radiological Society of North America/Fuji Film Seed Grant Award
  • 1995 Outstanding Recent Alumnus Award, University of Wisconsin- Platteville
  • 1994 Cancer Research Award, Ladies Auxilliary VFW, Iowa Chapter
  • 1993-94 Central Investment Fund for Research Enhancement, Vice President for Research, The University of Iowa
  • 1992-93 NIH/NRSA Postdoctoral Training Grant Recipient, Pharmacology and Toxicology, University of Arizona
  • 1991 International Congress of Radiation Research Student Travel Award.
  • 1989-91 NIH/NRSA Predoctoral Training Grant Recipient, Human Cancer Biology, University of Wisconsin
  • 1989-90 Radiation Research Society Student Travel Award
  • 1984 Human Oncology Special Fellowship, University of Wisconsin- Madison
  • 1982 Leo E. Boebel Memorial Biology Scholarship, University of Wisconsin-Platteville


  • PhD Human Cancer Biology, University of Wisconsin-Madison 1991
  • BS Chemistry, University of Wisconsin-Platteville, 1983 (Magna cum laude)

Post-Graduate Education

  • The University of Arizona, Department of Radiation Oncology, Arizona Cancer Center, Postdoctoral Research Associate, 1991-1992.
  • The University of Arizona, Department of Pharmacology & Toxicology,Arizona Cancer Center, NIH/NRSA Postdoctoral Trainee, 1992-1993
Research areas
  • Emeritus