Fall 2001

12:00-1:00, Wednesdays

Room B180, Med Labs
Contact: garry-buettner@uiowa.edu Tel 319/335-6749

August 29, 2001
Presenter: Mike McCormick, PhD
Paper: Gong et al (2001) Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kB PNAS 98: 9599-9604.

This paper can be found at the following website: http://www.pnas.org/cgi/reprint/98/17/9599.pdf

September 5, 2001
Presenter: Freya Schafer, PhD
Paper: Antunes F, Cadenas E. (2001) Cellular titration of apoptosis with steady state concentrations of H2O2: submicromolar levels of H2O2 induce apoptosis through Fenton chemistry independent of the cellular thiol state FRBM 30 (9): 1008-1018.

This paper can be found at the following website: http://www.elsevier.nl/locate/freeradbiomed?menu=cont&label=Table

September 12, 2001
Presenter: Christine Weydert
Paper: Bernard D et al. (2001) Antiproliferative and antiapoptotic effects of cRel may occur withing the same cells via the up-regulation of manganese superoxide dimutase Cancer Res 61: 2656-2664.

This paper can be found at the following website: http://cancerres.aacrjournals.org/cgi/reprint/61/6/2656.pdf

September 19, 2001
Presenter: Eric Kelley
Garban HJ, Bonavida B. (2001) Nitric oxide disrupts H2O2-dependent activation of nuclear factor kB J Biol Chem 276: 8918-8923.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/276/12/8918.pdf

September 26, 2001
Presenter: Kelly Andringa
Paper: Pervin S, Singh R, Chaudhuri G. (2001) Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): Potential role of cyclin D1. PNAS 98: 3583-3588.

This paper can be found at the following website: http://www.pnas.org/cgi/reprint/98/6/3583.pdf

October 3, 2001
Presenter: Jeff Kirsch
Paper: Jo SH et al. (2001) Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+-dependent isocitrate dehydrogenase. J Biol Chem 276: 16168-16176.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/276/19/16168.pdf

October 10, 2001
Presenter: Jun Luo
Paper: Kim SY, Kwon OJ, Park JW. (2001) Inactivation of catalase and superoxide disutase by singlet oxygen derived from photoactivated dye. Biochimie 83(5): 437-444.

October 17, 2001
Presenter: Dr. Michael Knudson
Paper: Cumming RC et al. (2001) Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1. Nature Medicine 7: 814-820.

October 24, 2001
Presenter: Dr. Prabhat Goswami
Paper: Davis CA et al. (2001) A coding region determinant of instability regulates levels of manganese superoxide dismutase mRNA. J Biol Chem 276: 37317-37326.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/276/40/37317.pdf

October 31, 2001
Presenter: K. Reszka
Paper: Bruck TB et al. (2001) Mechanism of nitrite-stimulated catalysis by lactoperoxidase. Eur J Biochem 268: 3214-3222.

This paper can be found at the following website: http://www.blackwell-synergy.com/member/institutions/processpaid.asp?content id=ejb.2001.1&filetype=pdf&article=111025&year=&journal=

November 7, 2001
Presenter: Shawn Flanagan
Paper: Sturtz LA et al. (2001) A fraction of yeast CuZn-Superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. J Biol Chem 276: 38084-38089.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/276/41/38084.pdf

November 14, 2001
No Presentation: Oxygen Society

November 21, 2001
No Presentation: Thanksgiving

November 28, 2001
Presenter: Eric Kelley
Paper: Nicholoson B et al (2001) Sustained Nitric Oxide Production in Macrophages Requires the Arginine Transporter CAT2. J Biol Chem 276: 15881-15885, 2001.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/276/19/15881.pdf

December 5, 2001
Presenter: Dr. Brad Britigan
Paper: Caltagirone A et al. (2001) Modulation of cellular iron metabolism by hydrogen peroxide. Effects of H2O2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts. J Biol Chem 276: 19738-19745.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/276/23/19738.pdf

December 12
Presenter: Sujatha Venkataraman
Paper: Haddad JJ and Land SC. (2001) A non-hypoxic, ROS-sensitive pathway mediates TNF-a-dependent regulation of HIF-1a. FEBS Lett. 505: 269-274.

This paper can be found at the following website: http://www.elsevier.nl/febs/164/23/32/00025235.pdf