Fall 2006

12:00-1:00, Wednesdays

Room B180, Med Labs
Contact: garry-buettner@uiowa.edu Tel 319/335-6749

August 23
Presenter: Dr. Garry Buettner
Paper: Hopper RK, Carroll S, Aponte AM, et al. (2006) Mitochondrial Matrix Phosphoproteome: Effect of Extra Mitochondrial Calcium. Biochemistry 45(8):2524 - 2536. <Link>

August 30
Presenter: Dr. Shawn Flanagan
Paper: Wu DC, Re DB, Nagai M, Ischiropoulos H, Przedborski S. (2006) The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proc Natl Acad Sci U S A. 103(32):12132-12137.<Link>

September 6
Presenter: Dr. Garry Buettner
Paper: Thomas DD, Ridnour LA, Espey MG, Donzelli S, Ambs S, Hussain SP, Harris CC, DeGraff W, Roberts DD, Mitchell JB, and Wink DA. (2006) Superoxide Fluxes Limit Nitric Oxide-induced Signaling. J. Biol. Chem. 281:25984-25993.<Link>

September 13
Presenter: Kjerstin Owens
Paper: Han D, Antunes F, Canali R, Rettori D, Cadenas E. (2003) Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem. 278(8):5557-5563.<Link>

September 20
Presenter: Dr. Douglas Spitz
Paper: Chen YR, Chen CL, Zhang L, Green-Church KB, Zweier JL. (2005) Superoxide generation from mitochondrial NADH dehydrogenase induces self-inactivation with specific protein radical formation. J Biol Chem. 280(45):37339-37348.<Link>

September 27
Presenter: Adam Case
Paper: Chularojmontri L, Wattanapitayakul SK, Herunsalee A, Charuchongkolwongse S, Niumsakul S, Srichairat S. (2005) Antioxidative and cardioprotective effects of Phyllanthus urinaria L. on doxorubicin-induced cardiotoxicity. Biol Pharm Bull. 28(7):1165-1171.<Link>

October 4
Presenter: Dr. Garry Buettner

Paper: Steinbrenner H, Bilgic E, Alili L, Sies H, Brenneisen P. (2006) Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity. Free Radic Res. 40(9):936-943. <Link>

Paper: Background Reading: Burk, RF and Hill, KE. and Selenoprotein, P:. (2005) An extracellular protein with unique physical characteristics and a role in selenium homeostasis. Annu Rev Nutr. 25:215 - 235. <Link>

October 11
Presenter: Dr. Aliye Uc
Paper: Marinissen MJ, Tanos T, Bolos M, de Sagarra MR, Coso OA, Cuadrado A. (2006) Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor. J Biol Chem. 281(16):11332-11346.<Link>

October 18
Presenter: Dr. Garry Buettner
Paper: Schroder K, Vecchione C, Jung O, Schreiber JG, Shiri-Sverdlov R, van
Gorp PJ, Busse R, Brandes RP. (2006) Xanthine oxidase inhibitor
tungsten prevents the development of atherosclerosis in ApoE knockout
mice fed a Western-type diet. Free Radic Biol Med. 41(9):1353-1360.<Link>

October 25
Presenter: Mike Hitchler
Paper: Uthus EO, Brown-Borg HM. (2006) Methionine flux to transsulfuration is enhanced in the long living Ames dwarf mouse. Mech Ageing Dev. 127(5):444-450.<Link>

November 1
Presenter: Matt Zimmerman
Paper: .Ferri A, Cozzolino M, Crosio C, Nencini M, Casciati A, Gralla EB, Rotilio G, Valentine JS, Carri MT. (2006) Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials. Proc Natl Acad Sci U S A. 103(37):13860-13865.<Link>

November 8
Presenter: Oksana Zagorodna
Paper: Qin F, Yan C, Patel R, et al. (2006). Vitamins C and E attenuate apoptosis, beta-adrenergic receptor desensitization, and sarcoplasmic reticular Ca2+ ATPase downregulation after myocardial infarction. Free Radic Biol Med. 40(10):1827-1842. <Link>

November 15
Presenter: SFRBM, No Journal Club

November 22
Presenter: Thanksgiving, No Journal Club

November 29
Presenter: Suwimol Jetawattana
Paper: Berchner-Pfannschmidt U, Yamac H, Trinidad B, and Fandrey J. (2006) Nitric Oxide Modulates Oxygen Sensing By HIF-1 Dependent Induction of Prolyl Hydroxylase 2. J Biol Chem. 282(3):1788-1796. <Link>

December 6
Presenter: Sean Didion
Paper: Li M, Chiu JF, Mossman BT, Fukagawa NK. (2006) Down regulation of MnSOD through phosphorylation of FOXO3a by AKT in explanted VSMC from old rats. J Biol Chem. 281(52):40429-40439. <Link>