Fall 2007

12:00-1:00, Wednesdays

Room B180, Med Labs

Contact: garry-buettner@uiowa.edu Tel 319/335-6749

August 29

Presenter: Dr. Douglas Spitz
Paper: Erler JT, Bennewith KL, Nicolau M, Dornhöfer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ. (2006) Lysyl oxidase is essential for hypoxia-induced metastasis. Nature 440(7088):1222-1226. [Article]

Paper: Payne SL, Fogelgren B, Hess AR, Seftor EA, Wiley EL, Fong SF, Csiszar K, Hendrix MJ, Kirschmann DA. (2005) Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism. Cancer Res. 65(24):11429-11436. [Article]

September 5

Presenter: Yueming Zhu
Paper: Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S. (2007) Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med. 13(6):688-694. [Article]

September 12

Presenter: Kjerstin Owens
Paper: Lacza Z, Kozlov AV, Pankotai E, Csordás A, Wolf G, Redl H, Kollai M, Szabó C, Busija DW, Horn TF. (2006) Mitochondria produce reactive nitrogen species via an arginine-independent pathway. Free Radic Res. 40(4):369-378. (Article)

September 19

Presenter: Melissa Fath
Paper: Dadachova E, Bryan RA, Huang X, Moadel T, Schweitzer AD, Aisen P, Nosanchuk JD, Casadevall A. (2007) Ionizing radiation changes the electronic properties of melanin and enhances the growth of melanized fungi. PLoS ONE. 2:e457. [Article]

September 26

Presenter: Dr. Garry Buettner
Paper: Gao YT, Roman LJ, Martásek P, Panda SP, Ishimura Y, Masters BS. (2007) Oxygen metabolism by endothelial nitric oxide synthase. J Biol Chem. 282:28557-28565. [Article]

October 3

Presenter: Dr. Nukhet Aykin-Burns
Paper: Szeto SS, Reinke SN, Sykes BD, Lemire BD. (2007) Ubiquinone-binding site mutations in the saccharomyces cerevisiae succinate dehydrogenase generate superoxide and lead to the accumulation of succinate. J Biol Chem. [Epub ahead of print]. [Article]

October 10

Presenter: Leena Chauhduri
Paper: Banjac A, Perisic T, Sato H, Seiler A, Bannai S, Weiss N, Kölle P, Tschoep K, Issels RD, Daniel PT, Conrad M, Bornkamm GW. (2007) The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death. Oncogene. [Epub ahead of print [Article]

October 17

Presenter: Disha Dayal
Paper: Castello PR, David PS, McClure T, Crook Z, Poyton RO. (2006) Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic
conditions: implications for oxygen sensing and hypoxic signaling in eukaryotes. Cell Metab. 3(4):277-287. [Article]

October 24

Presenter: Suwimol Jetawattana
Paper: Demicheli V, Quijano C, Alvarez B, Radi R. (2007) Inactivation and nitration of human superoxide dismutase (SOD) by fluxes of nitric oxide and superoxide. Free Radic Biol Med. 42(9):1359-1368. [Article]

October 31

Canceled due to FRRB Lunch

November 7

Presenter: Dr. Prabhat Goswami
Paper: Lee S, Jeong SY, Lim WC, Kim S, Park YY, Sun X, Youle RJ, Cho H. (2007) Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence. J Biol Chem. 282(31):22977-22983. [Article]

November 14

Presenter: NO FRJC, SFRBM Conference

November 21

Presenter: No FRJC, Thanksgiving Week

November 28

Presenter: Jim Jacobus
Paper: Liedvogel M, Maeda K, Henbest K, Schleicher E, Simon T, Timmel CR, Hore PJ, Mouritsen H. (2007) Chemical magnetoreception: bird cryptochrome 1a is excited by blue light and forms long-lived radical-pairs. PLoS ONE2(10):e1106. [Article]
Paper: Banerjee R, Schleicher E, Meier S, Viana RM, Pokorny R, Ahmad M, Bittl R, Batschauer A. (2007) The signaling state of Arabidopsis cryptochrome 2 contains flavin semiquinone. J Biol Chem. 282(20):14916-14922. [Article]

December 5

Presenter: Venkat Venkatesha
Paper: Barbouti A, Amorgianiotis C, Kolettas E, Kanavaros P, Galaris D. (2007) Hydrogen peroxide inhibits caspase-dependent apoptosis by inactivating procaspase-9 in an iron-dependent manner. Free Radic Biol Med. 43(10):1377-1387. [Article]

December 12

Presenter: Dr. Jennifer Nickerson-Gass
Paper: Kumar A, Wu H, Collier-Hyams LS, Hansen JM, Li T, Yamoah K, Pan ZQ, Jones DP, Neish AS. (2007) Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO J. 26(21):4457-4466. [Article]