Spring 2001

12:00-1:00, Wednesdays

Room B180, Med Labs
Contact: garry-buettner@uiowa.edu Tel 319/335-6749

January 17, 2001
Presenter: Eric Kelley
Paper: Beltran B et al. (2000) The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death. PNAS 96: 14602-14607.

This paper can be found at the following website: http://www.pnas.org/cgi/reprint/97/26/14602

January 24, 2001
Presenter: Shawn Flanagan
Paper: Bal-Price A and Brown GC. (2000) Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria. J Neurochem 75: 1455-1464.

January 31, 2001
Presenter: Larry Oberley
Lee AC et al. (1999) Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J Biol Chem 274: 7936-7940.

February 7, 2001
Presenter: Jeff Kirsch
Paper: Liochev SI and Fridovich I. (2000) Copper- and Zinc-containing Superoxide Dismutase Can Act as a Superoxide Reductase and a Superoxide Oxidase. J Biol Chem 275: 38482-38485.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/275/49/38482.pdf

Nieto N et al. (2000) Ethanol and arachidonic acid increase a2(I) collagen expression in rat hepatic stellate cells overexpressing cytochrome P450 2E1. J Biol Chem. 275: 20136-20145

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/275/26/20136.pdf

February 14, 2001
Presenter: Mike McCormick
Paper: Arlandson M et al. (2001) Eosinophil peroxidase oxidation of thiocyanate. J Biol Chem 276: 215-224

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/276/1/215.pdf

February 21, 2001
Presenter: Prabhat Goswami
Paper: Bouton C & Demple B. (2000) Nitric oxide-inducible expression of heme oxygenase-1 in human cells: translation-independent stabilization of the mRNA and evidence for direct action of nitric oxide. J Biol Chem 275: 32688-32693.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/275/42/32688.pdf

February 28, 2001
Presenter: Maher Abdalla

March 7, 2001
Presenter: Sabina Peters
Paper: Chandel NS et al. (2000) Redox regulation of p53 during hypoxia. Oncogene 19: 3840-3848.

March 14, 2001
No Presentation: Spring Break

March 21, 2001
Presenter: Iman Ahmad
Paper: Raha S et al. (2000) Superoxides from Mitochondrial Complex III: The role of manganese superoxide dismutase. Free Radic Biol Med 29: 170-180.

This paper can be found at the following website: http://www.elsevier.com/locate/freeradbiomed?menu=cont&label=Search

March 28, 2001
Presenter: Christine Darby
Paper: Drane P et al. (2001) Reciprocal down-regulation of p53 and SOD2 gene expression - implication in p53 mediated apoptosis. Oncogene. 20:430-439.

April 4, 2001
Presenter: Meredith Preuss
Paper: Choi J et al. (2000) Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice. J Biol Chem 275: 3693-3698.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/275/5/3693.pdf

April 11, 2001
Presenter: Min Wang
Paper: Chen C et al. (2001) Regulation of glut1 mRNA by Hypoxia-inducible Factor-1. J Biol Chem 276: 9519-9525.

This paper can be found at the following website: http://www.jbc.org/cgi/reprint/276/12/9519.pdf

April 18, 2001
Presenter: Jeff Kirsch
Paper: Liu L et al. (2001) A metabolic enzyme for s-nitrosothiol conserved from bacteria to humans. Nature 410:490-494.

April 25, 2001
Presenter: Jianfang Hu
Paper: Sakamoto H et al. (2000) Involvement of phospholipid hydroperoxide glutathione peroxidase in the modulation of prostaglandin D2 synthesis. J Biol Chem 275: 40028-40035.

May 2, 2001
Presenter: Rick Domann
Paper: Hirota K and Semenza GL. (2001) Rac1 activity is required for the activation of Hypoxia-Inducible Factor 1. J Biol Chem . In press.