Spring 2003

12:00-1:00, Wednesdays

Room B180, Med Labs
Contact: garry-buettner@uiowa.edu Tel 319/335-6749

January 22, 2003
Presenter: Garry R. Buettner, PhD
Paper: Baranano DE, Rao M, Ferris CD, Snyder SH. (2002) Biliverdin reductase: A major physiologic cytoprotectant. Proc Natl Acad Sci. 99:16093-16098.

January 29, 2003
Presenter: Freya Schafer, PhD
Paper: Nkabyo YS. Ziegler TR. Gu LH. Watson WH. Jones DP. (2002) Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells. Am J Physiol - Gastrointestinal & Liver Physiology. 283:G1352-1359

February 5, 2003
Presenter: Kelly Andringa
Paper: Moellering DR, Levonen AL, Go YM. (2002) Induction of glutathione synthesis by oxidized low-density liprotein and 1-palmitoyl-2-arachidonyl phosphatidylscholine: protection against quinone-mediated oxidative stress. Biochem J. 362:51-59.

February 12, 2003
Presenter: Lei Yu
Paper: Brenneisen P, Blaudschun R, Gille J. (2003) Essential role of an activator protein-2 (AP-2)/specificity protein 1 (sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes. Biochem J. 369:341-349.

February 19, 2003
Presenter: Michael McCormick, PhD
Paper: Kanayama A, Inoue JI, Sugita-Konishi Y. (2002) Oxidation of IkBa at methionine 45 is one cause of taurine chloramine-induced inhabition of NF-kB activation. J Biol Chem. 277(27):24049-24056.

February 26, 2003
Presenter: Xiaomei Zheng
Paper: Ho JCM, Zheng S, Comhair SAA. (2001) Differential expression of manganese superoxide dismutase and catalase in lung cancer. Cancer Research. 61:8578-8585.

March 5, 2003
Presenter: Gang Niu
Paper: Gouaze V, Andrieu-Abadie N, Cuvillier O. (2002) Glutathione peroxidase-1 protects from CD95-induced apoptosis J of Biol Chem. 277(45): 42867-42874.

March 12, 2003
Presenter: Lingjie Zhao
Paper: Pak JH, Manevich Y, Kim HS, Feinstein SI. (2002) An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells J of Biol Chem 277(51): 49927-49934.

March 19, 2003
No Presentation: Spring Break

March 26, 2003
Presenter: Carolyn Fisher
Paper: Mayo JC, Sainz RM, Atolin I, Harrera F. (2002) Melatonin regulation of antioxidant enzyme gene expression. Cell. Mol. Life Sci. 59: 1706-1713.

March 26, 2003
Presenter: Dr. Buettner
Paper: Li H, Samouilov A, Liu X, Zweier JL. (2003) Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate. Reduction: evaluation of its role in nitrite and nitric oxide generation in anoxic tissues. Biochemistry. 42: 1150-1159.

April 2, 2003
Presenter: Min Wang
Paper: Schafer G, Cramer T, Suske G, Kemmner W, Wiedenmann B, Hocker M. (2003) Oxidative Stress Regulates Vascular Endothelial Growth Factor-A Gene Transcription through Sp1- and Sp3-dependent Activation of Two Proximal GC-rich Promoter Elements. J. of Biol. Chem. 278:8190-8198.

April 9, 2003
Presenter: Sultana Banulescu
Paper: Andreassen OA, Ferrante RJ, Klivenyi P, Lkien AM, Dedeoglu A. (2001) Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. Experimental Neurology. 168:356-363.

April 16, 2003
Presenter: Dr. Douglas Spitz
Paper: Yankovskaya V, Horsefield R, Tornroth S, Luna-Chavez C, Miyoshi H, Leger C, Byrne B, Cecchini G, Iwata S. (2003) Architecture of succinate dehydrogenase and reactive oxygen generation. Science. 299:700-704.

April 23, 2003
Presenter: Dr. Prabhat Goswami
Paper: Bai J, Cederbaum AI. (2003) Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53. J. of Biol. Chem. 278(7):446-4667.

April 30, 2003
Presenter: Carolyn Fisher
Paper: Mayo JC, Sainz RM, Atolin I, Harrera F. (2002) Melatonin regulation of antioxidant enzyme gene expression. Cell. Mol. Life Sci. 59: 1706-1713.

May 7, 2003
Presenter: Dr. Buettner
Paper: Yu Z, Persson HL, Eaton JW, Brunk UT. (2003) Intralysosomal iron: a major determinant of oxidant-induced cell death Free Radical Biology and Medicine. Free Radical Biology and Medicine. 34(10):1243-1252.
Persson HL, Yu Z, Tirosh O, Eaton JW, Brunk UT. (2003) Prevention of oxidant- induced cell death by lysosomotropic iron chelators. Free Radical Biology and Medicine. 34(10):1295-1305.

May 14, 2003
No Presentation: Finals Week