Spring 2006

12:00-1:00, Wednesdays

Room B180, Med Labs
Contact: garry-buettner@uiowa.edu Tel 319/335-6749

January 18
Presenter: Dr. Garry Buettner
Paper: Blackstone E, Morrison M, and Roth MB. (2005) H2S induces a suspended animation-like state in mice. Science 308(5721):518-518.<Link>

Paper: Doeller JE, Isbell TS, Benavides G, et al. (2005) Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues. Anal Biochem. 341(1):40-51.<Link>

January 25
Presenter: Dr. Matthew Zimmerman
Paper: Rizzardini M, Mangolini A, Lupi M, et al. (2005) Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells. J Neurol Sci. 232(1-2):95-103.<Link>

February 1
Presenter: Oksana Zagorodna
Paper: Li Q, Sato EF, Kira Y, et al. (2006) A possible cooperation of SOD1 and cytochrome c in mitochondria-dependent apoptosis. Free Radic Biol Med. 40(1):173-81.<Link>

February 8
Presenter: Annie Liu
Paper: Yarian CS, Toroser D, and Sohal RS. (2006) Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice. Mech Ageing Dev. 127(1):79-84.<Link>

February 15
Presenter: Tanja Hadzic
Paper: Kleinbongard P, Dejam A, Lauer T, et al. (2006) Plasma nitrite concentrations reflect the degree of endothelial dysfunction in humans. Free Radic Biol Med. 40(2):295-302.<Link>

February 22
Presenter: Dr. Galina Kramarenko
Paper: Tu, BP, Kudlicki A, Rowicka M, and McKnight SL. (2005) Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes. Science 310:1152-1158.<Link>

March 1
Presenter: Dr. Yunxia O'Malley
Paper: Han D, Canali R, Garcia J, et al. (2005) Sites and mechanisms of aconitase inactivation by peroxynitrite: modulation by citrate and glutathione. Biochemistry 44(36):11986-96.<Link>

March 8
Presenter: Dr. Douglas Spitz
Paper: Santos JH, Meyer JN, Skorvaga M, et al. (2004) Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell. 3(6):399-411.<Link>

March 15
Presenter: No Class, Spring Break

March 22
Presenter: Dr. Sean Didion
Paper: Madamanchi NR, Moon SK, Hakim ZS, et al. (2005) Differential activation of mitogenic signaling pathways in aortic smooth muscle cells deficient in superoxide dismutase isoforms. Arterioscler Thromb Vasc Biol. 25(5):950-956.<Link>

March 29
Presenter: Research Week Poster Session
Paper: No FRJC

April 5
Presenter: Dr. Nukhet Aykin-Burns
Paper: Rapino C, Bianchi G, Di Giulio C, et al. (2005) HIF-1alpha cytoplasmic accumulation is associated with cell death in old rat cerebral cortex exposed to intermittent hypoxia. Aging Cell 4(4):177-85.<Link>

April 12
Presenter: Suwimol Jetawattana
Paper: Maranchie JKand Zhan Y. (2005) Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma. Cancer Res. 65(20):9190-9193.<Link>

April 19
Presenter: Kjerstin Owens
Paper: James AM, Cocheme HM, Smith RA, and Murphy MP. (2005) Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem. 280(22):21295-312.<Link>

April 26
Presenter: Chang-Ming Chen
Paper: Pletjushkina OY, Fetisova EK, Lyamzaev KG, Ivanova OY, et al. (2006) Hydrogen Peroxide Produced Inside Mitochondria Takes Part in Cell-to-Cell Transmission of Apoptotic Signal. Biochemistry (Mosc). 71(1):60-7. <Link>

May 3
Presenter: Dr. Garry Buettner
Paper: Kelley EE, Hock T, Khoo NK, Richardson GR, et al. (2006) Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells. Free Radic Biol Med. 40(6):952-959. <Link>