Free Radical Journal Club, The University of Iowa
Spring 2018, 11:30-12:30, Mondays, Room B180, Med Labs
Contact: Tel 319/335-8014

January 15, 2018
Presenter: No Journal Club, holiday, MLK Jr. Day

January 29, 2018
Presenter: Collin Heer
Paper: Viswanathan VS, Ryan MJ, Dhruv HD, Gill S, Eichhoff OM, Seashore-Ludlow B, Kaffenberger SD, Eaton JK, Shimada K, Aguirre AJ, Viswanathan SR, Chattopadhyay S, Tamayo P, Yang WS, Rees MG, Chen S, Boskovic ZV, Javaid S, Huang C, Wu X, Tseng YY, Roider EM, Gao D, Cleary JM, Wolpin BM, Mesirov JP, Haber DA, Engelman JA, Boehm JS, Kotz JD, Hon CS, Chen Y, Hahn WC, Levesque MP, Doench JG, Berens ME, Shamji AF, Clemons PA, Stockwell BR, Schreiber SL. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Nature. 2017 Jul 27;547(7664):453-457.  PMID: 28678785; PMCID: PMC5667900.
doi: 10.1038/nature23007.

Paper: Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition. Nature. 2017 Nov 9;551(7679):247-250. PMID: 29088702.
doi: 10.1038/nature24297.

February 12, 2018
Presenter: Adrienne Gibson
Paper: Khan SJ, Abidi SNF, Skinner A, Tian Y, Smith-Bolton RK. The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling. PLoS Genet. 2017 Jul 28;13(7):e1006937. PMID: 28753614; PMCID: PMC5550008.
doi: 10.1371/journal.pgen.1006937

February 26, 2018
Presenter: Kelly Falls
Paper:Bhattacharjee A, Yang H, Duffy M, Robinson E, Conrad-Antoville A, Lu YW, Capps T, Braiterman L, Wolfgang M, Murphy MP, Yi L, Kaler SG, Lutsenko S, Ralle M. The Activity of Menkes Disease Protein ATP7A Is Essential for Redox Balance in Mitochondria. J Biol Chem. 2016 Aug 5;291(32):16644-58. PMID: 27226607; PMCID: PMC4974379.
doi: 10.1074/jbc.M116.727248

March 12, 2018
Presenter: Spring Break, No Journal Club

March 26, 2018
Presenter: Michelle Tamplin
Paper: Özer MA, Polat N, Özen S, Parlakpınar H, Ekici K, Polat A, Vardı N, Tanbek K, Yildiz A. Effects of Molsidomine on Retinopathy and Oxidative Stress Induced by Radiotheraphy in Rat Eyes. Curr Eye Res. 2017 May;42(5):803-809. PMID: 27897441.
doi: 10.1080/02713683.2016.1238943.

April 9, 2018
Presenter: Paige Kluz
Paper: Fitzgerald JC, Zimprich A, Carvajal Berrio DA, Schindler KM, Maurer B, Schulte C, Bus C, Hauser AK, Kübler M, Lewin R, Bobbili DR, Schwarz LM, Vartholomaiou E, Brockmann K, Wüst R, Madlung J, Nordheim A, Riess O, Martins LM, Glaab E, May P, Schenke-Layland K, Picard D, Sharma M, Gasser T, Krüger R. Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease. Brain. 2017 Sep 1;140(9):2444-2459. PMID: 29050400.
doi: 10.1093/brain/awx202.

April 23, 2018
Presenter: Cam Cushing
Paper: van Bergen JMG, Li X, Quevenco FC, Gietl AF, Treyer V, Meyer R, Buck A, Kaufmann PA, Nitsch RM, van Zijl PCM, Hock C, Unschuld PG. Simultaneous quantitative susceptibility mapping and Flutemetamol-PET suggests local correlation of iron and β-amyloid as an indicator of cognitive performance at high age. Neuroimage. 2018 Mar 13;174:308-316. PMID: 29548847.
doi: 10.1016/j.neuroimage.2018.03.021.