CURRENT TOPICS IN RADIATION AND CANCER BIOLOGY (77:548)

The University of Iowa

Fall 2004

11:30-12:30, Mondays

Room B180, Med Labs

Contact: nukhet-aykin-burns@uiowa.edu Tel 319-335-8025

August 23, 2004
Presenter: Dr. Goswami
Paper: Elstrom RL, Bauer DE, Buzzai M, et al. (2004) Akt stimulates aerobic glycolysis in cancer cells. Cancer Res. 64:3892-3899.[DOI Article]

August 30, 2004
Presenter: Dr. Spitz
Paper: Yang Y, Dieter MZ, Chen Y, Shertzer HG, et al. (2002) Initial Characterization of the Glutamate-Cysteine Ligase Modifier Subunit Gclm(/) Knockout Mouse. J. Biol. Chem. 277(51):49446-49452.[DOI Article]

September 6, 2004
Presenter: No Journal Club, Labor Day

September 13, 2004
Presenter: Michael Hitchler
Paper: Yin L, Huang L, Kufe DW. (2004) MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. J Biol Chem. Epub ahead of print.[DOI Article]

September 20, 2004
Presenter: Carolyn Fisher
Paper: Zhu W, Chen Y, Dutta A. (2004) Rereplication by Depletion of Geminin Is Seen Regardless of p53 Status and Activates a G2/M Checkpoint. Mol. Cell. Biol. 24:7140-7150.[DOI Article]

September 27, 2004
Presenter: Kjerstin Owens
Paper: Yang J., Chen Z., Liu Y. et al. (2004) Altered DNA Polymerase Expression in Breast Cancer Cells Leads to a Reduction in DNA Replication Fidelity and a Higher Rate of Mutagenesis. Cancer Research 64:5597-5607.[DOI Article]

October 4, 2004
Presenter: Chang-Ming Chen
Paper: Prithivirajsingh S, Story MD, Bergh SA, et al. (2004) Accumulation of the common mitochondrial DNA deletion induced by ionizing radiation. FEBS Lett.571(1-3):227-32. [DOI Article]

October 11, 2004
Presenter: Ling Xiao
Paper: Abid MR, Schoots IG, Spokes KC, et al. (2004) VEGF-mediated induction of MnSOD occurs through redox-dependent regulation of forkhead and Ikappa B/NF-kappa B. J Biol Chem. Epub ahead of print.[DOI Article]

October 18, 2004
Presenter: Nukhet Aykin-Burns
Paper: Kluza J, Marchetti P, Gallego M-A, et al. (2004) Mitochondrial proliferation during apoptosis induced by anticancer agents:effects of doxorubicin and mitoxantrone on cancer and cardiac cells. Oncogene 23:7018-7030. [DOI Article]

October 25, 2004
Presenter: Amanda Kalen
Paper: Hassan KA, Ang KK, El-Naggar AK et al. (2002) Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma. Cancer Res. 62:6414-6417.[DOI Article]

November 1, 2004
Presenter: Disha Dayal
Paper: Ichikawa K, Takeuchi Y, Yonezawa S, et al. (2004) Antiangiogenic photodynamic therapy (PDT) using Visudyne causes effective suppression of tumor growth. Cancer Letters 205(1):39-48.[DOI Article]

November 8, 2004
Presenter: Kelly Andringa
Paper: Yamada M, Tomida A, Yun J, et al. (1999) Cellular sensitization to cisplatin and carbonplatin with decreased removal of platinum-DNA adduct by glucose-regulated stress. Cancer Chemother Pharmacol 44:59-64.[DOI Article]
November 15, 2004
Presenter: Suwimol Jetawattana
Paper: Li J, Zhang X, Sejas DP, et al. (2004) Hypoxia-induced nucleophosmin protects cell death through inhibition of p53. J. Biol. Chem. 279(40):41275-41279.[DOI Article]

November 22, 2004
Presenter: No Class, Thanksgiving week

November 29, 2004
Presenter: Dr. Douglas Spitz
Paper: Zhang X, Kon T, Wang H, et al. (2004) Enhancement of Hypoxia-Induced Tumor Cell Death In vitro and Radiation Therapy In vivo by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α. Cancer Res. 64:8139-8149.[DOI Article]

December 6, 2004
Presenter: Dr. Nukhet Aykin-Burns
Paper: Mori K, Shibanuma M, and Nose K. (2004) Invasive Potential Induced under Long-Term Oxidative Stress in Mammary Epithelial Cells. Cancer Research 64:7464-7472.[DOI Article]