The University of Iowa

Fall 1999

11:30-12:30, Mondays

Room B180, Med Labs

Contact: Tel 319-335-8025

August 23, 1999
Organizational Meeting

August 30, 1999
Presenter: Mike Robbins
Paper: "Blockade of the Vascular Endothelial Growth Factor Stress Response Increases the Antitumor Effects of Ionizing Radiation" by Gorski et al. from Cancer Res. 59:3374-3378 (1999)

September 06, 1999
No Presentation: Labor Day

September 13, 1999
Presenter: J.W. Osborne
Paper: "Radiation-Induced DNA Base Damage Detected in Individual Aerobic and Hypoxic Cells with Endonuclease III and Formamidopyrimidine-glycosylase" by Banáth et al. from Radiat. Res. 151:550-558 (1999)

September 20, 1999
Presenter: Jason Duex
Paper: "Suppression of Ultraviolet Irradiation-induced Apoptosis by Over-expression of Focal Adhesion Kinase in Madin-Darby Canine Kidney Cells" by Chan et al. from J. Biol. Chem. 274:26901-26906 (1999)

September 27, 1999
Presenter: Robert Walters
Paper: "Reversible Tumorigenesis by MYC in Hematopoietic Lineages" by Felsher and Bishop from Molecular Cell, 4:199-207, 1999.

October 04, 1999
Presenter: Christine Darby
Paper: "Antisense Bcl-2 Oligodeoxynucleotides Inhibit Progression to Androgen- Independence after Castration in the Shionogi Tumor Model" by Miyake et al. from Cancer Res. 59:4030-4034(1999)

October 11, 1999
Presenter: Tongrong He
Paper: "Inhibition of RNA polymerase II as a trigger for the p53 response" by Ljungman et al. from Oncogene 18:583-592 (1999).

October 18, 1999
Presenter: Nick Khoo
Paper: "p73 is a human p53-related protein that can induce apoptosis" by C.A. Jost et al. from Nature 189:191-194 (1997).

October 25, 1999
Presenter: Meredith Preuss
Paper: "A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy" by Komarov et al. from Science 285:17733-1737 (1999).

November 01, 1999
Presenter: Garry Buettner
Paper: "Mitochondrial phospholipid hyproperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway" by Nomura et al. from J. Biol. Chem. 274:29294-29302 (1999).

November 08, 1999
Presenter: Chunhong Zhu
Paper: "An intronic NF-k B element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-a and interleukin-1b " by Xu et al. from DNA and Cell Biology 18:709-722 (1999).

November 14, 1999
Presenter: Iman Ahmad
Paper: "The suppression of metastases and the change in host immune response after low-dose total-body irradiation in tumor-bearing rats" by Hashimoto et al. from Radiat. Res. 151:717-7724 (1999).

November 22, 1999
Presenter: Weiling Zhao
Paper: "Smad4/DPC4 Silencing and Hyperactive Ras Jointly Disrupt Transforming Growth Factor-b Antiproliferative Responses in Colon Cancer Cells" by Calonge and Massagué from J. Biol. Chem., 247:33637-33643 (1999)

November 29, 1999
Presenter: Ying Zhang
Paper: "Ataxia Telangiectasia Mutated Deficiency Affects Growth but not Radio- sensitivity" by Gosink et al. from Cancer Res., 59:5294-5298 (1999)

December 06, 1999.
Presenter: Hong Duan
Paper: "Epigenetic phenotypes distinguish microsatellite-stable and –unstable colorectal cancers" by Kuismanen et al. from PNAS 96:12661-12666 (1999).