The University of Iowa

Fall 2000

11:30-12:30, Mondays

Room B180, Med Labs
Contact: Tel 319-335-8025

August 21, 2000
Organizational Meeting

August 28, 2000
Presenter: Doug Spitz
Paper: "Reactive Oxygen Species Generated at Mitochondrial Complex III Stabilize Hypoxia- inducible Factor-1a during Hypoxia" by Chandel et al. in J. Biol. Chem. 275:25130- 25138 (2000)

September 04, 2000
No Presentation

September 11, 2000
Presenter: Mike Robbins
Paper: "Unique Anti-Activator Protein-1 Activity of Retinoic Acid Receptor β1" by Lin et al. from Cancer Res. 60:3271-3280 (2000)

September 18, 2000
Presenter: Christine Weydert
Paper: “Plasmid/Liposome Transfer of the Human Manganese Superoxide Dismutase Transgene Prevents Ionizing Irradiation-Induced Apoptosis in Human Esophagus Organ Explant Culture" by Epperly et al. From Int. J. Cancer (Radiat. Oncol. Invest.) 90:128-137 (2000)

September 25, 2000
Presenter: Rick Domann
Paper: "High frequency of hypermethylation at the 14-3-3 s locus leads to gene silencing in breast cancer" by Ferguson et al., from PNAS, May 23, 2000, 97:6049-6054 (2000).

October 02, 2000
Presenter: Meredith Preuss
Paper: "Cell Cycle Arrest and Apoptosis of Melanoma Cells by Docosahexaenoic Acid: Association with decreased pRb phosphorylation" " by Albino et al from Cancer Res. 60:4139-4145 (2000).

October 09, 2000
Presenter: Tongrong He
Paper: "A Redox Mechanism Controls Differential DNA Binding Activities of Hypoxia- inducible Factor (HIF) 1α and the HIF-like Factor" by Lando et al. in J. Biol. Chem. 275:4618-4627 (2000)

October 16, 2000
Presenter: Jianfang Hu
Paper: "Disruption of Redox Homeostatis in Tumor Necrosis Factor-Induced Apoptosis in a Murine Hepatocyte Cell Line" by Pierce et al. From Am. J. Pathology 157:221-236 (2000).

October 23, 2000
Presenter: Maher Abdalla
Paper: "Enhanced DNA Binding and Activation of Transcription Factors NF-κB and AP-1 by Acetaldehyde I HEPG2 Cells" by Roman et al. from J. Biol Chem. 275:14684-14690( (2000).

October 30, 2000
Presenter: Sabina Peters
Paper: "Metallothionein induction in human CNS in vitro: neuroprotection from ionizing radiation" by Cai et al. From Int. J. Radiat. Biol. 76:1109-1117 (2000).

November 06, 2000
Presenter: Iman Ahmad
Paper: "Glucose starvation reduces IGF-1 mRNA in tumor cells: Evidence for an effect on mRNA stability" by Wang et al. From Biochem Biophys. Res Commun 269:336-346 (2000).

November 13, 2000
Presenter: Sherry Timmons
Paper: "The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress- induced cell death" by Kurokawa et a. from The EMBO Journal 19:2958-2968 (2000).

November 27, 2000
Presenter: Jun Luo
Paper: "Ultraviolet-A-Induced Transactivation of the Vascular Endothelial Growth Factor Gene in HaCaT Keratinocytes Conveyed by Activator Protein-2 Transcription Factor" by Gille et al. from The Journal of Investigative Dermatology, Vol. 115:30-36 (2000).

Presenter: Maher Abdalla,
Paper: "Enhanced DNA Binding and Activation of Transcription Factors NF-κB and AP-1 by Acetaldehyde in HEPG2 Cells" by Román et al. from J. Biological Chemistry, Vol. 275:14684-14690 (2000).

December 04, 2000
Presenter: Sherry Rovinsky
Paper: "Direct recruitment of N-myc to target gene promoters" by Mac et al., from Mol. Carciogenesis 29:76-86 (2000).