The University of Iowa

Fall 2001

11:30-12:30, Mondays

Room B180, Med Labs
Contact: Tel 319-335-8025

August 27, 2001
Organizational Meeting

September 03, 2001
No Presentation: Labor Day

September 10, 2001
Presenter: Jeff Kirsch
Paper: "Hydrogen peroxide mediates the cell growth and transormation caused by the mitogenic oxidase Nox1" by Arnold et al.from PNAS. 98(10):5550-5555 (2001)

September 17, 2001
Presenter: Maher Abdalla
Paper: "Hepatitis C virus core protein activates nuclear factor kB-dependent signaling through tumor necrosis factor receptor-associated factor" by Yoshida et al. from JBC 276(19):16399-16405 (2001)

September 24, 2001
Presenter: Eric Kelley
Paper: "Intersection of Interferon and hypoxia signal transduction pathways in nitric oxide-induced tumor apoptosis" by Tendler et al., from Cancer Res., 61:3682-3688 (2001).

October 01, 2001
Presenter: Meredith Preuss
Paper: "Cell Cycle Arrest and Apoptosis of Melanoma Cells by Docosahexaenoic Acid:Association with decreased pRb phosphorylation" by Albino et al from Cancer Res. 60:4139-4145 (2000).

October 08, 2001
Presenter: Christine Weydert
Paper: "A Redox Mechanism Controls Differential DNA Binding Activities of Hypoxia-inducible Factor (HIF) 1a and the HIF-like Factor" by Lando et al. in J. Biol. Chem. 275:4618-4627 (2000)

October 15, 2001
Presenter: Dr. Larry Oberley
Paper: "Overexpression of Manganese Superoxide Dismutase Suppresses Tumor Formation by Modulation of Activator Protein-1 Signaling in a Multistage Skin Carcinogenesis Model" by Zhao et al. from Cancer Res. 61:6082-6088 (2001)

October 22, 2001
Presenter: Dr. Bill Osborne
Paper: "Molecular Events in Radiation Transformation" by Syljuåsen, Krolewski and Little from Radiat. Res. 155:215-221 (2001)

November 05, 2001
Presenter: Dr. Rick Domann
Paper: "A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF" by Bruick and McKnight from Sciencexpress.

November 12, 2001
Presenter: Eric Kelley
Paper: "Nitric oxide production by tumour tissue: impact on the response to photo- dynamic therapy" by Korbelik et al. from Brit. J. Cancer 82:1835-1843 (2000)

November 26, 2001
Presenter: Dr. Prabhat Goswami
Paper: "ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks" by Burma et al. from JBC 276(45):42462-42467(2001)

December 03, 2001
Presenter: Dr. Hannah Zhang
Paper: "Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics" by Melov et al. from J. Neuroscience, 21:8348-8353 (2001)

December 10, 2001
Presenter: Dr. Kyle Brown
Paper: "Regulation of cell growth by redox-mediated extracellular proteolysis of platelet-derived growth factor receptor ?" by Okuyama et al. from JBC, 276(30):28274-28380 (2001)