The University of Iowa

Fall 2002

11:30-12:30, Mondays

Room B180, Med Labs

Contact: Tel 319-335-8025

September 9, 2002
Presenter: Kelly Andringa
Paper: "Reversal of Cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistance phenotype" Biochemical Pharmacology (2002) 63: 1699-1707. [DOI Article]

September 16, 2002
Presenter: Garry Buettner
Paper: "Dynamic regulation of metabolism and respiration by endogenously produced nitric oxide protects against oxidative stress" PNAS (2001) 98:11575-11580

September 23, 2002
Presenter: Wenqing Sun
Paper: "Manganese Superoxide Dismutase (SOD2) Inhibits Radiation-Induced Apoptosis by Stabilization of the Mitochondrial Membrane." Radiation Research (2002) 157: 568-577 [DOI Article]

September 30, 2002
Presenter: Christine Weydert
Paper: Replication-Selective Herpes Simplex Virus Type 1 Mutant Therapy of Cervical Cancer Is Enhanced by Low-Dose Radiation Human Gene Therapy (2002) 13:627-639

October 7, 2002
Presenter: Sarita Menon
Paper: "A growth factor-dependant nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression." EMBO Journal (2002) 21: 3390-3401

October 14, 2002
No Presentation: Prostate Cancer Meeting:

October 21, 2002
Presenter: Gang Niu
Paper: "Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription" The Embo Journal (2002) 21: 5195-5205

October 28, 2002
Presenter: Prabhat Goswami
Paper: "Regulation of Peroxiredoxin I activity by Cdc2-mediated phosphorylation" J. Biological Chemistry (2002).277: 25370-25376 [DOI Article]

November 4, 2002
Presenter: Ken Dornfeld
Paper: "The Ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis" Oncogene (2002) 21: 7195-7204 [DOI Article]

November 11, 2002
Presenter: Sharon Hu
Paper: "The Alternative Reading Frame Tumor Suppressor Inhibits Growth through p21-dependent and p21-independent Pathways1" Cancer Research (2001) 61: 3145-3150 [DOI Article]

November 18, 2002
Presenter: Kimberly Krager
Paper: "Antitumor Effect of TAT-Oxygen-dependent Degradation-Caspase-3 Fusion Protein Specifically Stabilized and Activated in hypoxic Tumor Cells" Cancer Research (2002) 62: 2013-2018 [DOI Article]

November 25, 2002
Presenter: Min Wang
Paper: "Modulation of chromatin organization by RH-3, a preparation of Hippophae rhamnoides, a possible role in radioprotection" Molecular and Cellualr Biochemistry (2002) 238: 1-9

December 2, 2002
Presenter: Mike James
Paper: "Myc suppression of the p21/Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage" Nature (2002) 419: 729-734

December 9, 2002
Presenter: Douglas Spitz
Paper: "Mutation in the Glucose-6-phosphate Dehydrogenase Gene Leads to Inactivation of Ku DNA End Binding during Oxidative Stress" The Journal of Biological Chemistry (2002) 277: 9929-9935 [DOI Article]