The University of Iowa

Fall 2003

11:30-12:30, Mondays

Room B180, Med Labs

Contact: Tel 319-335-8025

August 25, 2003
Presenter: Dr. Douglas Spitz
Paper: “Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defense and tumour suppression” Nature (2003) 424:561-565.

September 1, 2003
No Journal Club, Holiday

September 8, 2003
Presenter: Dr. Prabhat Goswami
Paper: “RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation” PNAS (2003) 100(14):8354-8359

September 15, 2003
Presenter: Kelly Andringa
Paper: "Ply (L-glutamic acid)-paclitaxel conjugate is a potent enhancer of tumor radiocurability” Int. J. Radiation Oncology Biol. Phys. (2003) 55(3):707-712

September 22, 2003
Presenter: Benjamin Slane
Paper: “Increased Expression of Mitochondrial Peroxiredoxin-3 (Thioredoxin Peroxidase-2) Protects Cancer Cells Against Hypoxia and Drug-Induced Hydrogen Peroxide-Dependent Apoptosis” Mol. Cancer Res. (2003) 1:682-689.

September 29, 2003
Presenter: Hualei Li
Paper: “The Retinoblastoma Protein Binds the Promoter of the Survival Gene bcl-2 and Regulates Its Transcription in Epithelial Cells through Transcription Factor AP-2” Molecular and Cellular Biol. (2003) 22(22):7877-7888.

October 6, 2003
Presenter: Jingru Liu
Paper: “Resistance to tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis in rat hepatoma cells expressing TNF-alpha is linked to low antioxidant enzyme expression” J. Biol. Chem. (2003) 278(32):29626-29632.

October 13 2003
Presenter: Sarita Menon
Paper: “Catalase Activity Is Regulated by c-Abl and Arg in the Oxidative Stress Response” J. Biol. Chem. (2003) 278(32):29667-29675.

October 20, 2003
Presenter: Lei Yu
Paper: “p73 expression induces both accumulation and activation of wt-p53 independent of the p73 transcriptional activity” Oncogene (2003) 22(35):5451-5456.

October 27, 2003
Presenter: Sultana Banulescu
Paper: “Proteomic Analysis of Intestinal Epithelial Cells Expressing Stabilized ß-Catenin” Cancer Research (2003) 63(15):4641-4647.

November 3, 2003
Presenter: Carolyn Fisher
Paper: “Cell Cycle-Dependent Expression of Phosphorylated Histone H2AX: Reduced Expression in Unirradiated but not X-Irradiated G1-Phase Cells” Radiation Research (2003) 169(6):759–767.

November 10, 2003
Presenter: Kim Krager
Paper: “Nonradioactive Iodide Effectively Induces Apoptosis in Genetically Modified Lung Cancer Cells” Cancer Research (2003) 63(16): 5065-5072.

November 17, 2003
Presenter: Haris Hamsakutty
Paper: “Tumor response to radiotheraphy regulated by endothelial cell apoptosis” Science. (2003) 300:1155-1159

November 24, 2003
Presenter: No Meeting, Oxygen Society

December 1, 2003
Presenter: Christine Weydert
Paper “p27Kip1 Inhibition of GRB2-SOS Formation Can Regulate Ras Activation” Mol. Cellular Biol. (2003) 23(11):3735-3752

December 8, 2003
Presenter: Ehab Sarsour
Paper “Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases” PNAS. (2000) 97(8):4291-4296

December 15, 2003
Presenter: Zhen Gao
Paper “Glioma-associated Hyaluronan Induces Apoptosis in Dendritic Cells via Inducible Nitric Oxide Synthase” Cancer Research (2002) 62(9): 2583-2591