Cancer Biology Journal Club, The University of Iowa

Fall 2015, 11:30-12:30, Mondays, Room B180, Med Labs

Contact: apollina-goel@uiowa.edu Tel 319/384-4754

August 31, 2015
Presenter: Cameron Cushing
Paper: Deistung A, Schweser F, Wiestler B, Abello M, Roethke M, Sahm F, Wick W, Nagel AM, Heiland S, Schlemmer HP, Bendszus M, Reichenbach JR, Radbruch A. Quantitative susceptibility mapping differentiates between blood depositions and calcifications in patients with glioblastoma. PLoS One. 2013;8(3):e57924.
doi: 10.1371/journal.pone.0057924. PMID: 23555565; PMCID: PMC3605431.

September 14, 2015
Presenter: Kelly Falls
Paper: Allensworth JL, Evans MK, Bertucci F, Aldrich AJ, Festa RA, Finetti P, Ueno NT, Safi R, McDonnell DP, Thiele DJ, Van Laere S, Devi GR. Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer. Mol Oncol. 2015 Jun;9(6):1155-68. doi: 10.1016/j.molonc.2015.02.007. PMID: 25769405; PMCID: PMC4493866

September 28, 2015
Presenter: Madelyn Espinosa-Cotton
Paper: Benevides L, da Fonseca DM, Donate PB, Tiezzi DG, De Carvalho DD, de Andrade JM, Martins GA, Silva JS. IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment. Cancer Res. 2015 Sep 15;75(18):3788-99. doi: 10.1158/0008-5472.CAN-15-0054. PMID: 26208902.

October 12, 2015
Presenter: Adrienne Klinger
Paper: Tan AS, Baty JW, Dong LF, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV. Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab. 2015 Jan 6;21(1):81-94. doi: 10.1016/j.cmet.2014.12.003. PMID: 25565207.

October 26, 2015
Presenter: Shane Solst
Paper:  Zhang Y, Wang SX, Ma JW, Li HY, Ye JC, Xie SM, Du B, Zhong XY. EGCG inhibits properties of glioma stem-like cells and synergizes with temozolomide through downregulation of P-glycoprotein inhibition. J Neurooncol. 2015 Jan;121(1):41-52. doi: 10.1007/s11060-014-1604-1. PMID: 25173233.

November 9, 2015
Presenter: Paige Kluz
Paper: Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, Leyrat AA, Sim S, Okamoto J, Johnston DM, Qian D, Zabala M, Bueno J, Neff NF, Wang J, Shelton AA, Visser B, Hisamori S, Shimono Y, van de Wetering M, Clevers H, Clarke MF, Quake SR. Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat Biotechnol. 2011 Nov 13;29(12):1120-7. doi: 10.1038/nbt.2038. PMID: 22081019; PMCID: PMC3237928.

November 23, 2015 -- THANKSGIVING,
No Journal Club
 

December 7, 2015
Presenter: John Lafin
Paper: Wang MT, Holderfield M, Galeas J, Delrosario R, To MD, Balmain A, McCormick F. K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling. Cell. 2015 Nov 19;163(5):1237-1251. doi: 10.1016/j.cell.2015.10.041. PMID: 26590425.

December 14, 2015
Presenter: Justin Wilkes
Paper: Hemachandra LP, Shin DH, Dier U, Iuliano JN, Engelberth SA, Uusitalo LM, Murphy SK, Hempel N. Mitochondrial Superoxide Dismutase Has a Protumorigenic Role in Ovarian Clear Cell Carcinoma. Cancer Res. 2015 Nov 15;75(22):4973-84. doi: 10.1158/0008-5472.CAN-14-3799. PMID: 26359457 PMCID: PMC4651777.