Cancer Biology Journal Club, The University of Iowa
Fall 2015, 11:30-12:30, Mondays, Room B180, Med Labs
 Contact: douglas-spitz@uiowa.edu  Tel 319/335-8019
 

August 29, 2016
Presenter: Shane Solst
Paper: Latorre-Pellicer A, Moreno-Loshuertos R, Lechuga-Vieco AV, Sánchez-Cabo F, Torroja C, Acín-Pérez R, Calvo E, Aix E, González-Guerra A, Logan A, Bernad-Miana ML, Romanos E, Cruz R, Cogliati S, Sobrino B, Carracedo Á, Pérez-Martos A, Fernández-Silva P, Ruíz-Cabello J, Murphy MP, Flores I, Vázquez J, Enríquez JA. Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing. Nature. 2016 Jul 28;535(7613):561-5. PMID: 27383793.

September 12, 2016
Presenter: Madelyn Espinosa-Cotton
Paper: Chittezhath M, Dhillon MK, Lim JY, Laoui D, Shalova IN, Teo YL, Chen J, Kamaraj R, Raman L, Lum J, Thamboo TP, Chiong E, Zolezzi F, Yang H, Van Ginderachter JA, Poidinger M, Wong AS, Biswas SK. Molecular profiling reveals a tumor-promoting phenotype of monocytes and macrophages in human cancer progression. Immunity. 2014 Nov 20;41(5):815-29. PMID: 25453823.
doi: 10.1016/j.immuni.2014.09.014

September 26, 2016
Presenter: Paige Kluz
Paper: Chae YC, Vaira V, Caino MC, Tang HY, Seo JH, Kossenkov AV, Ottobrini L, Martelli C, Lucignani G, Bertolini I, Locatelli M, Bryant KG, Ghosh JC, Lisanti S, Ku B, Bosari S, Languino LR, Speicher DW, Altieri DC. Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming. Cancer Cell. 2016 Aug 8;30(2):257-72.
PMID: 27505672. doi: 10.1016/j.ccell.2016.07.004.

October 10, 2016
Presenter: Kelly Falls
Paper:  Pan M, Reid MA, Lowman XH, Kulkarni RP, Tran TQ, Liu X, Yang Y, Hernandez-Davies JE, Rosales KK, Li H, Hugo W, Song C, Xu X, Schones DE, Ann DK, Gradinaru V, Lo RS, Locasale JW, Kong M. Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation. Nat Cell Biol. 2016 Oct;18(10):1090-101. PMID: 27617932.
doi: 10.1038/ncb3410.

October 24, 2016
Presenter: Adrienne Klinger
Paper: Cui J, Xia T, Xie D, Gao Y, Jia Z, Wei D, Wang L, Huang S, Quan M, Xie K. HGF/Met and FOXM1 form a positive feedback loop and render pancreatic cancer cells resistance to Met inhibition and aggressive phenotypes. Oncogene. 2016 Sep 8;35(36):4708-18. PMID: 26876216; PMCID: PMC4985506.
doi: 10.1038/onc.2016.14.

November 7, 2016
Presenter: Dr. Ryan Sheehy
Paper: Lee JK, Phillips JW, Smith BA, Park JW, Stoyanova T, McCaffrey EF, Baertsch R, Sokolov A, Meyerowitz JG, Mathis C, Cheng D, Stuart JM, Shokat KM, Gustafson WC, Huang J, Witte ON. N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. Cancer Cell. 2016 Apr 11;29(4):536-47. PMID: 27050099; PMCID: PMC4829466.
doi: 10.1016/j.ccell.2016.03.001.

November 21, 2016
Presenter:  Thanksgiving, No journal club

December 5, 2016
Presenter: Dr. Melissa Fath
Paper: Chan N, Willis A, Kornhauser N, Ward MM, Lee SB, Nackos E, Seo BR, Chuang E, Cigler T, Moore A, Donovan D, Vallee Cobham M, Fitzpatrick V, Schneider S, Wiener A, Guillaume-Abraham J, Anjom E, Zelkowitz R, Warren JD, Lane ME, Fischbach C, Mittal V, Vahdat L. Influencing the tumor microenvironment: Phase 2 Study of Copper depletion with tetrathiomolybdate in high risk breast cancer and preclinical models of lung metastases. Clin Cancer Res. 2016 Oct 21. pii: clincanres.1326.2016. PMID: 27769988.
doi: 10.1158/1078-0432.CCR-16-1326.