Cancer Biology Journal Club, The University of Iowa
Fall 2018, 11:30-12:30, Every Other Monday, Room B180, Med Labs
Contact: Tel 319/335-8019

August 27, 2018
Presenter: Dr. Frederick Domann
Paper:  Cong J, Wang X, Zheng X, Wang D, Fu B, Sun R, Tian Z, Wei H. Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression. Cell Metab. 2018 Aug 7;28(2):243-255.e5. PMID: 30033198.
doi: 10.1016/j.cmet.2018.06.021.

Commentary Paper:  Isaacson B, Mandelboim O. Sweet Killers: NK Cells Need Glycolysis to Kill Tumors. Cell Metab. 2018 Aug 7;28(2):183-184. PMID: 30089237.
doi: 10.1016/j.cmet.2018.07.008.

September 10, 2018
Presenter: Dr. Prabhat Goswami
Paper:Obrist F, Michels J, Durand S, Chery A, Pol J, Levesque S, Joseph A, Astesana V, Pietrocola F, Wu GS, Castedo M, Kroemer G. Metabolic vulnerability of cisplatin-resistant cancers. EMBO J. 2018 Jul 13;37(14). pii: e98597. PMID: 29875130; PMCID: PMC6043854.

September 24, 2018
Presenter: No journal club, RRS Meeting

October 8, 2018
Presenter: Dr. Ann Miller
Paper: Chao Y, Xu L, Liang C, Feng L, Xu J, Dong Z, Tian L, Yi X, Yang K, Liu Z. Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses. Nature biomedical engineering. 2018 Aug;2:611-621.

October 22, 2018
Presenter: Collin Heer
Paper:Santidrian AF, Matsuno-Yagi A, Ritland M, Seo BB, LeBoeuf SE, Gay LJ, Yagi T, Felding-Habermann B. Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression. J Clin Invest. 2013 Mar;123(3):1068-81. PMID: 23426180; PMCID: PMC3582128.
doi: 10.1172/JCI64264

November 5, 2018
Presenter: Dr. Xiangbing Meng
Paper: Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, Sirohi K, Li X, Wei Y, Lee H, Zhuang L, Chen G, Xiao ZD, Hung MC, Chen J, Huang P, Li W, Gan B. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018 Sep 10. PMID: 30202049.

November 19, 2018
Presenter:  No Journal Club, Thanksgiving

December 3, 2018
Presenter: Dr. Douglas Spitz
Paper: Shin D, Kim EH, Lee J, Roh JL. Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer. Free Radic Biol Med. 2018 Dec;129:454-462. PubMed PMID: 30339884.
doi: 10.1016/j.freeradbiomed.2018.10.426