CURRENT TOPICS IN RADIATION AND CANCER BIOLOGY (FRRB:6008)
SCHEDULE OF PRESENTATIONS
Fall 2025 (Director: Dr. Douglas Spitz)
11:30 AM - 12:30 PM EVERY OTHER MONDAY Room 1180 Med Labs

Presentations for Fall 2025

August 25, 2025

Presenter: Douglas Spitz

Papers: Huang J, Min S, Hong R, Zou M, Zhou D. High-dose Vitamin C inhibits PD-L1 expression by activating AMPK in colorectal cancer. Immunobiology. 2025 May;230(3):152893. doi: 10.1016/j.imbio.2025.152893. Epub 2025 Mar 21. PMID: 40139125.

Yu C, Min S, Lv F, Ren L, Yang Y, Chen L. Vitamin C inhibits the growth of colorectal cancer cell HCT116 and reverses the glucose-induced oncogenic effect by downregulating the Warburg effect. Med Oncol. 2023 Sep 13;40(10):297. doi: 10.1007/s12032-023-02155-x. PMID: 37702811.

September 08, 2025

Presenter: Ellen Voigt

Paper: Choi HJ, Jhe YL, Kim J, Lim JY, Lee JE, Shin MK, Cheong JH. FoxM1-dependent and fatty acid oxidation-mediated ROS modulation is a cell-intrinsic drug resistance mechanism in cancer stem-like cells. Redox Biol. 2020 Sep; 36:101589. doi: 10.1016/j.redox.2020.101589. Epub 2020 May 29. PMID: 32521504; PMCID: PMC7286985.

September 22, 2025

Presenter: Kyle Current

Paper: Fefelova N, Wongjaikam S, Pamarthi SH, Siri-Angkul N, Comollo T, Kumari A, Garg V, Ivessa A, Chattipakorn SC, Chattipakorn N, Gwathmey JK, Xie LH. Deficiency of mitochondrial calcium uniporter abrogates iron overload-induced cardiac dysfunction by reducing ferroptosis. Basic Res Cardiol. 2023 May 25;118(1):21. doi: 10.1007/s00395-023-00990-7. PMID: 37227592; PMCID: PMC10589903.

October 6, 2025

Presenter: Rachel Kehrberg

Paper: Guo L, Cui C, Zhang K, Wang J, Wang Y, Lu Y, Chen K, Yuan J, Xiao G, Tang B, Sun Y, Wu C. Kindlin-2 links mechano-environment to proline synthesis and tumor growth. Nat Commun. 2019 Feb 19;10(1):845. doi: 10.1038/s41467-019-08772-3. PMID: 30783087; PMCID: PMC6381112.

October 20, 2025

Presenter: Michael Schrodt

Paper: Sousa, J.A., Callejas, B.E., Wang, A. et al. GPx1 deficiency confers increased susceptibility to ferroptosis in macrophages from individuals with active Crohn’s disease. Cell Death Dis 15, 903 (2024). https://doi.org/10.1038/s41419-024-07289-y

November 3, 2025

Presenter: Ziyu Wang

Paper: Wang L, Zhong S, Fan X, Xu Y, Wang M, Xu Y, Cai Y, Cao Z, Ye Z, Wen L, Wei P. Glutathione reductase underlies the stability of mutant p53 by antagonizing protein glutathionylation. Redox Biology, Volume 81, 2025, 103522, ISSN 2213-2317, https://doi.org/10.1016/j.redox.2025.103522.
 

November 17, 2025

Presenter: Asad Lak

Paper:

December 1, 2025

Presenter: 

Paper: