CURRENT TOPICS IN RADIATION AND CANCER BIOLOGY (77:548)

The University of Iowa

Spring 1998

11:30-12:30, Mondays

Room B180, Med Labs

Contact: nukhet-aykin-burns@uiowa.edu Tel 319-335-8025

January 19, 1998
No Presentation: MARTIN LUTHER KING CONVOCATION:

January 26, 1998
Organizational meeting

February 02, 1998
Presenter: Mike Robbins
Paper: "Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model" by Arap et al., from Science 279:377-380 (1998)

February 09, 1998
Presentation: Meredith Preuss
Paper: "Modulation of Apoptosis and Bcl-2 Expression by Prostaglandin E2 in Human Colon Cancer Cells" by Sheng et al., from Cancer Res. 58:362-366 (1998).

February 16, 1998
Presenter: Nick Khoo
Paper: "Efficacy of Hyperthermia and Polyunsaturated Fatty Acids on Experimental Carcinoma" by Kokura et al. from Cancer Res. 57:2200-2202, June 1 (1997),
"Gamma Linolenic Acid Regulates Expression of Maspin and the Motility of Cancer Cells" by Jiang et al. from Biochem. Biophys. Res. Commun. 237:639-644 (1997)

February 23, 1998
Presenter: Chun-Hong Zhu
Paper: "Inhibition of DNA Methylation by 5-Aza-2’-deoxycytidine Suppresses the Growth of Human Tumor Cell Lines" by C. Bender et al. from Cancer Research 58:95- 101, January 1 (1998).

March 02, 1998
Presenter: Weiling Zhao
Paper: "Inhibition of Caspases by Cytokine Response Modifier A Blocks Androgen Ablation-mediated Prostate Cancer Cell Death in vivo" by S. Srikanth and A. Kraft from Cancer Research 58:834-839 (1998).

March 09, 1998
Presenter: Tongrong He
Paper: "CpG Methylation Inactivates the Transcriptional Activity of the Promoter of the Human p53 Tumor Suppressor Gene" by Schroeder and Mass, Biochem Biophys Res Commun 235:403-406 (1997),

"Sunlight Induces Pyrimidine Dimers Preferentially at 5-Methylcytosine Bases" by Tommasi et al., Cancer Res. 57:4727-4780 (1997).

March 16, 1998
No presentation: SPRING BREAK

March 23, 1998
Presenter: Eric Kelley
Paper: "Independent Pathways of p53 Induction by Cisplatin and X-rays in a Cisplatin- resistant Ovarian Tumor Cell Line" by Siddik et al., Cancer Res. 58:698-703 (1998)

March 30, 1998
Presenter: Garry Buettner
Paper: "UV-Irradiation Depletes Antioxidants and Causes Oxidative Damage in a Model of Human Skin" by M. Podda et al., Free Radical Biology Med. 24:55-65 (1998)

April 06, 1998
Presenter: Mike Robbins
Paper: "Cellular and Molecular Mechanisms of Radiation Inhibition of Restenosis. Part I: Role of the macrophage and platelet –derived growth factor" by Rubin et al. IJROBP 40:929-941 (1998).

April 13, 1998
No Presentation: Meeting of the Prostate Cancer Research Group

April 20, 1998
Presenter: Rick Domann
Paper: "Methylation of the BRCA1 Gene in Sporadic Breast Cancer" by Dobrovic and Simpfendorfer; and "A BRCA1 Mutant Alters G2-M Cell Cycle Control in Human Mammary Epithelial Cells" by Larson et al., in Cancer Research, Vol. 57, pp. 3347-3350 and 3351-3355, respectively, (1997)

April 27, 1998
RADIATION RESEARCH SOCIETY MEETING, Louisville, KY --- APRIL 24-29, 1998

May 04, 1998
Cancelled

May 11, 1998
Presenter: Bill Osborne
Paper: "Carbogen Breathing Increases 5-Fluorouracil Uptake and Cytotoxicity in Hypoxic Murine RIF-1 Tumors: A Magnetic Resonance Study In Vivo" by McSheehy et al., in Cancer Research, Vol. 58, pp. 1185-1194, (1998)