The University of Iowa

Spring 1999

11:30-12:30, Mondays

Room B180, Med Labs

Contact: Tel 319-335-8025

January 18, 1999

January 25, 1999
Presenter: Geoff Girnun
Paper: "Differentiation and reversal of malignant changes in colon cancer through PPARg " by Sarraf et al. (pp. 1046-1052), and "Activation of the peroxisome proliferator-activated receptor g promomtes the development of colon tumors in C57BL/6J-APCMin/+ mice" by Lefebvre et al. (pp. 1053-1057) from Nature Medicine, Vol. 4 (1998)

February 01, 1999
Presenter: Dr. Bill Osborne
Paper: "The relationships between p53-dependent apoptosis, inhibition of proliferation, and 5-fluorouracil-induced histopathology in murine intestinal epithelia" by D.M. Pritchard et al. from Cancer Res. 58:5453-5465 (1998).

February 08, 1999
Presenter: Dr. Mike Robbins
Paper: "Intratrachael injection of adenovirus containing the human MnSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis" by Epperly et al. in Int. J. Radiation Oncology Biol. Phys. Vol 43:169-181(1999)

February 15, 1999
Presenter: Dr. Shail Sahu
Paper: "Chemosensitization of glioblastoma cells to bis-dichloroethyl-nitrosourea with Dept. Surgery tyrphostin AG17" by Liang and Ullyatt in Clin. Cancer Res. 4:773-781, 1998.

February 22, 1999
Presenter: Meredith Preuss
Paper: "Ik Ba degradation is not a requirement for the X-ray-induced activation of nuclear factor k B in normal rat astrocytes and human brain tumour cells" by Raju et al. in Int. J. Radiat. Biol. 74:617-624, 1998.

February 29, 1999
Presenter: Dr. Garry Buettner
Paper: "Protection by vitamin C of loss of vitamin E in cultured rat hepatocytes" by Halpner et al. in Archives Biochem. Biophys., 359:305-309, 1998.

March 08, 1999
Presenter: Heather Adu-Sarkodie
Paper: "Interleukin 1a and tumor necrosis factor a stimulate autocrine amphiregulin expression and proliferation of human papillomavirus-immortalized and carcinoma-derived cervical epithelial cells" by Woodworth et al., in Proc. Natl. Acad. Sci. USA, 92:2840-2844, 1995.

March 15, 1999
No Presentation: SPRING BREAK

March 22, 1999
Presenter: Geoff Girnun
Paper: "Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO" by Gelmetti et al. in Mol. Cell. Biology 18:7185-7191, 1998.

March 29, 1999
Presenter: Shimin Wei 
Paper: "Retinoic acid increases tyrosine phosphorylation of focal adhesion kinase and paxillin in MCF-7 human breast cancer cells" by Zhu et al. in Cancer Res., 59:85- 90, 1999.

April 12, 1999
Presenter: Dr. Garry Buettner
Paper: "Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells" by Lee et al. in J. Biol. Chem. 273:5294-5299, 1998.

April 19, 1999
Presenter: Nick Khoo
Paper: "Peroxisome proliferator-activated receptor g ligands are potent inhibitors of ang- iogenesis in vitro and in vivo" by Xin et al. in J Biol Chem, 274:9116-9121, 1999.

April 26, 1999
Presenter: Dr. Rick Domann
Paper: "Radioisotope concentrator gene therapy using the sodium/iodide symporter gene" by Mandell et al. in Cancer Res. 59:661-668, 1999.