CURRENT TOPICS IN RADIATION AND CANCER BIOLOGY (77:548)

The University of Iowa

Spring 2002

11:30-12:30, Mondays

Room B180, Med Labs

Contact: nukhet-aykin-burns@uiowa.edu Tel 319-335-8025

January 28, 2002
Presenter: J.W. Osborne
Organizational meeting and Selected Aspects of 50 years of the Radiation Sciences

February 04, 2002
Presenter: Kelly Andringa
Paper: "Targeting superoxide dismutase to renal proximal tubule cells inhibits nephrotoxicity of cisplatin and increases the survival of cancer-bearing mice" by Nishikawa et al. in Cancer Letts. 171 (2001) 133-138 [DOI Article]

February 11, 2002
Presenter: Sarita Menon
Paper: "Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice" by Peter et al. in EMBO 20(7):1538-1546 (2001).

February 18, 2002
Presenter: Garry Buettner
Paper: "Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels" by Kuppusamy et al. in Cancer Res. 62:307-312 (2002).[DOI Article]

February 25, 2002
Presenter: Lei Yu
Paper: "Induction of AP-2a expression by adenoviral infection involves inactivation of the AP-2rep transcriptional corepressor CtBP1*" by Schuierer et al. in Journal of Biological Chemistry 276:27944-27949 (2001).[DOI Article]

March 04, 2002
Presenter: Wenqing Sun
Paper: "Bcl-2 overexpression decreases BCNU sensitivity of a human glioblastoma line through enhancement of catalase activity" by Del Bufalo et al. in J. Cellular Biochemistry (2001) 83:473-483.[DOI Article]

March 11, 2002
Presenter: Sabina Peters
Paper: "Expression of Hypoxia-inducible Factor-1a: A Novel Predictive and Prognostic Parameter in the Radiotherapy of Oropharyngeal Cancer" by Aebersold et al. in Cancer Res. 61: 2911-2916, April 1, 2001.[DOI Article]

March 18, 2002
No Presentation: SPRING BREAK

March 25, 2002
Presenter: Ling Li
Paper: "Additional gene therapy with Ad5CMV-p53 enhanced the efficacy of radiotherapy in human prostate cancer cells". Sasaki R, et al. Int J Radiation Oncology Biol Phys. 51(5): 1336-1345 (2001)[DOI Article]

April 01, 2002
Presenter: Christine Weydert
Paper: "Overexpression of c-Myc Alters G1/S Arrest following Ionizing Radiation" by Joon-Ho Sheen and Robert B. Dickson, in Molecular and Cellular Biology, 22(6):1819-1833 (2002).

April 08, 2002
Presenter: Gang Niu
Paper: "Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo" by Doubrovin et al. (2001) in PNAS 98:9300-9305. [DOI Article]

April 15, 2002
Presenter: P.C. Goswami
Paper: "Two molecularly distinct G2/M checkpoints are induced by ionizing radiation" by Xu et al. in Mol. and Cell. Biol. 22:1049-1059 (2002).

April 22, 2002
Presenter: Rick Domann
Paper: "The mdm2 proto-oncogene sensitizes human medullary thyroid carcinoma cells to ionizing radiation," by Dilla et al. in Oncogene 21:2376-2386 (2002).

April 29, 2002
Presenter: Ehab Sarsour
Paper: "The Ataxia telangiectasia gene product is required for oxidative stress-induced G1 and G2 checkpoint function in human fibroblasts" by Shackelford et al. in J. Biol. Chem. 276(24):21951-21959 (2001).[DOI Article]

May 06, 2002
Presenter: Doug Spitz
Paper: "Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway" by Nomura et al. in J. Biol. Chem. 274(41):29294-29302 (1999).[DOI Article]