The University of Iowa

Spring 2005

11:30-12:30, Mondays

Room B180, Med Labs

Contact: Tel 319-335-8025

January 24, 2005
Presenter: Dr. Spitz
Paper: Ishii T, Yasuda K, Akatsuka A, et al. (2005) A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis. Cancer Res. 65(1):203-209.

January 31, 2005
Presenter: Dr. Goswami
Paper: Bakin RE and Jung MO. (2004) Cytoplasmic Sequestration of HDAC7 from Mitochondrial and Nuclear Compartments upon Initiation of Apoptosis. JBC 279(49):51218-51225. [DOI Article]

February 7, 2005
Presenter: Mike Hitchler
Paper: Liu JW, Chandra D, Rudd MD, et al. (2005) Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS. Oncogene 24:1-12.[DOI Article]

February 14, 2005
Presenter: Changbin Du
Paper: Rangarajan A, Hong SJ, Gifford A, Weinberg RA. (2004) Species- and cell type-specific requirements for cellular transformation. Cancer Cell 6(2):171-83.[DOI Article]

February 21, 2005
Presenter: Kelly Andringa
Paper: Williams KJ, Telfer BA, Brave S, et al. (2004) ZD6474, a Potent Inhibitor of Vascular Endothelial Growth Factor Signaling, Combined With Radiotherapy. AACR 10:8587-8593.[DOI Article]

February 28, 2005
Presenter: Kjerstin Owens
Paper: Laurent A, Nicco C, Chereau C, et al. (2005) Controlling tumor growth by modulating endogenous production of reactive oxygen species. Cancer Res. 65(3):948-956.[DOI Article]

March 7, 2005
Presenter: Dr. Domann
Paper: Xu RH, Pelicano H, Zhou Y, et al. (2005) Inhibition of Glycolysis in Cancer Cells: A Novel Strategy to Overcome Drug Resistance Associated with Mitochondrial Respiratory Defect and Hypoxia. Cancer Res. 65:613-621.[DOI Article]

March 14, 2005
Presenter: No class, Spring Break

March 21, 2005
Presenter: Matt Zimmerman
Paper: Zhao Y, Chaiswing L, Oberley TD, et al. (2005) A mechanism-based antioxidant approach for the reduction of skin carcinogenesis. Cancer Res. 65(4):1401-1405.[DOI Article]

March 28, 2005
Presenter: Dr. Douglas Spitz
Paper: Li H, Kantoff PW, Giovannucci E, et al. (2005) Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer. AACR 65(6):2498-2504.[DOI Article]

April 4, 2005
Presenter: Kate Pedersen
Paper: Li Z, Wang D, Messing EM, et al. (2005) VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1α. EMBO Reports 6(4):1-6.[DOI Article]

April 11, 2005
Presenter: Hualei Li
Paper: Brenner C, Deplus R, Didelot C, et al. (2004) Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J. 24(2):336-46.[DOI Article]

April 18, 2005
Presenter: Amanda Kalen
Paper: Janss AJ; Maity A; Tang C-B, et al. (2001) Decreased cyclin B1 expression contributes to G2 delay in human brain tumor cells after treatment with camptothecin. Neuro-Oncology 3(1):11-21.[DOI Article]

April 25, 2005
Presenter: Gang Niu
Paper: Covello KL, Simon MC, Keith B. (2005) Targeted replacement of hypoxia-inducible factor-1alpha by a hypoxia-inducible factor-2alpha knock-in allele promotes tumor growth. Cancer Res. 65(6):2277-86.[DOI Article]

May 2, 2005
Presenter: Kim Krager
Paper: Dwyer RM, Bergert ER, O'connor MK, Gendler SJ, Morris JC. (2005) In vivo radioiodide imaging and treatment of breast cancer xenografts after MUC1-driven expression of the sodium iodide symporter. Clin Cancer Res. 11(4):1483-9.[DOI Article]