CURRENT TOPICS IN RADIATION AND CANCER BIOLOGY (77:548)

The University of Iowa

Spring 2010

11:30-12:30, Mondays

Room B180, Med Labs

Contact: apollina-goel@uiowa.edu Tel 319-384-4754

Presentations for Spring 2010:

May 3, 2010
Presenter: Rick Domann
Paper: Zhang XW, Yan XJ, Zhou ZR, Yang FF, Wu ZY, Sun HB, Liang WX, Song AX, Lallemand-Breitenbach V, Jeanne M, Zhang QY, Yang HY, Huang QH, Zhou GB, Tong JH, Zhang Y, Wu JH, Hu HY, de Thé H, Chen SJ, Chen Z. (2010) Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML. Science. 328(5975):240-243.
[DOI Article]

January 25, 2010
Presenter: Dr. Douglas Spitz
Paper: Acharya MM, Christie LA, Lan ML, Donovan PJ, Cotman CW, Fike JR, Limoli CL. (2009) Rescue of radiation-induced cognitive impairment through cranial transplantation of human embryonic stem cells. Proc Natl Acad Sci U S A. 106(45):19150-5.
[DOI Article]

February 1, 2010
Presenter: Peter Scarbrough
Paper: Minor RK, Smith DL Jr, Sossong AM, Kaushik S, Poosala S, Spangler EL, Roth GS, Lane M, Allison DB, de Cabo R, Ingram DK, Mattison JA. (2009) Chronic ingestion of 2-deoxy-d-glucose induces cardiac vacuolization and increases mortality in rats. Toxicol Appl Pharmacol. [Epub ahead of print]
[DOI Article]

February 8, 2010
Presenter: Dr. Prabhat Goswami
Paper: Ahsan A, Hiniker SM, Davis MA, Lawrence TS, Nyati MK. (2009) Role of cell cycle in epidermal growth factor receptor inhibitor-mediated radiosensitization. Cancer Res. 2009 Jun 15;69(12):5108-14. PMCID: PMC2697971
[DOI Article]

February 15, 2010
Presenter: Maneesh Kumar
Paper: Ebi H, Sato T, Sugito N, Hosono Y, Yatabe Y, Matsuyama Y, Yamaguchi T, Osada H, Suzuki M, Takahashi T. (2009) Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers. Oncogene. 28(38):3371-9.
[DOI Article]

February 22, 2010
Presenter: Mitch Coleman
Paper: Lee JJ, Lee JH, Ko YG, Hong SI, Lee JS. (2010) Prevention of premature senescence requires JNK regulation of Bcl-2 and reactive oxygen species. Oncogene. 29(4):561-75.
[DOI Article]

March 1, 2010
Presenter: Gaowei Mao
Paper: Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH, Zhuang SM. (2009) Effects of MicroRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology. [Epub ahead of print] PMID: 20041405
[DOI Article]

March 8, 2010
Presenter: Jennifer Gass
Paper: Sánchez-Aragó M, Chamorro M, Cuezva JM. (2010) Selection of cancer cells with repressed mitochondria triggers colon cancer progression. Carcinogenesis. [Epub ahead of print] PMID: 20080835
[DOI Article]

March 15, 2010
Presenter: No Presentation Spring Break

March 22, 2010
Presenter: Lauren Wegman
Paper: Hussein D, Mo H. (2009) d-Dlta-tocotrienol-mediated suppression of the proliferation of human PANC-1, MIA PaCa-2, and BxPC-3 pancreatic carcinoma cells. Pancreas. 38(4):e124-36.
[DOI Article]

March 29, 2010
Presenter: Melissa Fath
Paper: Debeb BG, Xu W, Mok H, Li L, Robertson F, Ueno NT, Reuben J, Lucci A, Cristofanilli M, Woodward WA. (2010) Differential radiosensitizing effect of valproic acid in differentiation versus self-renewal promoting culture conditions. Int J Radiat Oncol Biol Phys. 76(3):889-95.
[DOI Article]

April 5, 2010
Presenter: Adam Case
Paper: Ammirante M, Luo JL, Grivennikov S, Nedospasov S, Karin M. (2010) B-cell-derived lymphotoxin promotes castration-resistant prostate cancer. Nature 64(7286):302-5.
[DOI Article]

April 12, 2010
Presenter: Tony Cyr
Talk: Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. (2010) Skp2 targeting suppresses tumorigenesis by arf-p53-independent cellular senescence. Nature. 464:374-379.
[DOI Article]

April 19, 2010
Presenter: Jordan Witmer
Paper: Wang SP, Wang WL, Chang YL, Wu CT, Chao YC, Kao SH, Yuan A, Lin CW, Yang SC, Chan WK, Li KC, Hong TM, Yang PC. (2009) p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nat Cell Biol. 11(6):694-704.
[DOI Article]

April 26, 2010
Presenter: Joshua Madsen
Paper: Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S, McDermott U, Azizian N, Zou L, Fischbach MA, Wong KK, Brandstetter K, Wittner B, Ramaswamy S, Classon M, Settleman J. (2010) A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell. 141(1):69-80.
[DOI Article]