Cancer Biology Journal Club, The University of Iowa
Spring 2017, 11:30-12:30, Mondays, Room B180, Med Labs
Contact: Tel 319/384-4754

January 23, 2017
Presenter: Paige Kluz
Paper: Di Biase S, Lee C, Brandhorst S, Manes B, Buono R, Cheng CW, Cacciottolo M, Martin-Montalvo A, de Cabo R, Wei M, Morgan TE, Longo VD. Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity. Cancer Cell. 2016 Jul, 11;30(1):136-46. PMID: 27411588.
doi: 10.1016/j.ccell.2016.06.005.

February 6, 2017
Presenter: Adrienne Klinger 
Paper: Little AC, Sham D, Hristova M, Danyal K, Heppner DE, Bauer RA, Sipsey LM, Habibovic A, van der Vliet A. DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties. Oncogenesis. 2016 Oct 3;5(10):e261.. PMID: 27694834; PMCID: PMC5117847.
doi: 10.1038/oncsis.2016.61

February 20, 2017
Presenter:  Kelly Falls
Paper: Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L, Benitah SA. Targeting metastasis-initiating cells through the fatty acid receptor CD36. Nature. 2017 Jan 5;541(7635):41-45. PMID: 27974793.
doi: 10.1038/nature20791.

March 6, 2017
Presenter: Collin Heer
Paper: Pusapati RV, Daemen A, Wilson C, Sandoval W, Gao M, Haley B, Baudy AR, Hatzivassiliou G, Evangelista M, Settleman J. mTORC1-Dependent Metabolic Reprogramming Underlies Escape from Glycolysis Addiction in Cancer Cells. Cancer Cell. 2016 Apr 11;29(4):548-62. PMID: 27052953.
doi: 10.1016/j.ccell.2016.02.018.

March 20, 2017
Presenter: Amanda Kalen
Paper Zhang Z, Lang J, Cao Z, Li R, Wang X, Wang W. Radiation-induced SOD2 overexpression sensitizes colorectal cancer to radiation while protecting normal tissue. Oncotarget. 2017 Jan 31;8(5):7791-7800. PubMed PMID: 27999194.
doi: 10.18632/oncotarget.13954.

April 3, 2017
Presenter:  Matt Alexander
Paper: Shen SM, Guo M, Xiong Z, Yu Y, Zhao XY, Zhang FF, Chen GQ. AIF inhibits tumor metastasis by protecting PTEN from oxidation. EMBO Rep. 2015 Nov;16(11):1563-80. PMID: 26415504; PMCID: PMC4641507.
doi: 10.15252/embr.201540536.

April 17, 2017, In lieu of our cancer biology journal club we will have a PhD presentation at 11:30am in 283 Seebohm EMRB.
Presenter: John Lafin
Title: "Methylseleninic Acid Induces Lipid Peroxidation and Sensitizes Head and Neck Cancer Cells to Radiation Therapy"

May 1, 2017
Presenter: Paul Akhenblit
Paper: Cramer SL, Saha A, Liu J, Tadi S, Tiziani S, Yan W, Triplett K, Lamb C, Alters SE, Rowlinson S, Zhang YJ, Keating MJ, Huang P, DiGiovanni J, Georgiou G, Stone E. Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. Nat Med. 2017 Jan;23(1):120-127. Epub 2016 Nov 21. PMID: 27869804; PMCID: PMC5218918.
doi: 10.1038/nm.4232.