CURRENT TOPICS IN RADIATION AND CANCER BIOLOGY FRRB:6008

SCHEDULE OF PRESENTATIONS

Spring 2026

Director: Dr. Douglas Spitz

11:30 AM - 12.30 PM EVERY OTHER MONDAY IN 1180 ML

Presentations for Spring 2026

January 19, 2026

No journal club, MLK Day

February 2, 2026

Presenter: Douglas Spitz

Paper: Ma S, Han Y, Gu R, Chen Q, Guo Q, Yue Y, Cao C, Liu L, Yang Z, Qin Y, Yang Y, Zhang K, Liu F, Liu L, Yang N, Hao J, Yang J, Yao Z, Mao X, Shi L. Auranofin attenuates TOPBP1-mediated ATR replication stress response and improves chemotherapeutic response in breast tumor models. J Clin Invest. 2025 Dec 15;135(24):e180106. doi: 10.1172/JCI180106. PMID: 41392982; PMCID: PMC12700547.

February 16, 2026

Presenter: Ellen Voigt

Paper: Carmona-Rodríguez L, Martínez-Rey D, Fernández-Aceñero MJ, González-Martín A, Paz-Cabezas M, Rodríguez-Rodríguez N, Pérez-Villamil B, Sáez ME, Díaz-Rubio E, Mira E, Mañes S. SOD3 induces a HIF-2α-dependent program in endothelial cells that provides a selective signal for tumor infiltration by T cells. J Immunother Cancer. 2020 Jun;8(1):e000432. doi: 10.1136/jitc-2019-000432. PMID: 32591431; PMCID: PMC7319787.

March 2, 2026

Presenter: Kyle Current

Paper: Cao Y, Vergnes L, Wang YC, Pan C, Chella Krishnan K, Moore TM, Rosa-Garrido M, Kimball TH, Zhou Z, Charugundla S, Rau CD, Seldin MM, Wang J, Wang Y, Vondriska TM, Reue K, Lusis AJ. Sex differences in heart mitochondria regulate diastolic dysfunction. Nat Commun. 2022 Jul 4;13(1):3850. doi: 10.1038/s41467-022-31544-5. PMID: 35787630; PMCID: PMC9253085.

March 16, 2026

No journal club, Spring Break

March 30, 2026

Presenter: Asad Lak

Paper: Guo X, Moynihan ZA, Driver J, Patel RV, Bhave VM, Maury EA, Knelson EH, Guo H, Lin JR, Coy SM, Wang A, Gupta S, Hoffman SE, Dunn IF, Dunn GP, Petti A, Choi BD, Choudhury A, Raleigh DR, Wei K, Reardon DA, Barbie D, Lederer JA, Santagata S, Bi WL. Meningioma microenvironment harbors a rich immune landscape that evolves with biological state. Neuro Oncol. 2026 Feb 2:noag022. doi: 10.1093/neuonc/noag022. Epub ahead of print. PMID: 41630100.

April 13, 2026

Presenter: Michael Schrodt

Paper: Chi Y, Song C, Jia Q, Zhang R, Sun F, Li Z, Jia Y, An X, Wang Z, Li J. A metal coordination polymer nanoparticle synergistically re-establishes acidosis and enhances chemodynamic therapy for Glioblastoma. Acta Biomater. 2025 Jan 15;192:290-301. doi: 10.1016/j.actbio.2024.11.042. Epub 2024 Nov 26. PMID: 39608659.

April 27, 2026

Presenter: Rachel Kehrberg

Paper: Ma L, Chen C, Zhao C, Li T, Ma L, Jiang J, Duan Z, Si Q, Chuang TH, Xiang R, Luo Y. Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer. Signal Transduct Target Ther. 2024 Mar 7;9(1):64. doi: 10.1038/s41392-024-01772-w. PMID: 38453925; PMCID: PMC10920667.